PU-WS13
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PU-WS13 속성
- 끓는 점
- 617.4±65.0 °C(Predicted)
- 밀도
- 1.47±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C(protect from light)
- 용해도
- DMF: 30 mg/mL,DMSO: 30 mg/mL,DMSO:PBS(pH7.2) (1:1): 0.5 mg/mL,Ethanol: 25 mg/mL
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 10.15±0.29(Predicted)
안전
PU-WS13 C화학적 특성, 용도, 생산
개요
PU-WS13 is an inhibitor of the heat shock protein family member and chaperone protein glucose-regulated protein 94 (GRP94; IC50 = 0.22 μM). It is selective for GRP94 over the chaperones Hsp90α, Hsp90β, and TRAP1 (IC50s = 27.3, 41.8, and 7.3 μM, respectively). PU-WS13 (0.5, 2.5, and 12.5 μM) induces apoptosis without increasing Hsp70 protein levels in HER2-overexpressing SK-BR-3, BT474, and MDA-MB-361 breast cancer cells. It also induces apoptosis and necrosis in multiple myeloma cells but does not induces cell death in pre-B leukemic cells.용도
PU-WS13 is a pharmaceutical agent used in the preparation go paralog=selective HSP90 inhibitors used in anti-tumor treatments.PU-WS13 준비 용품 및 원자재
원자재
준비 용품
PU-WS13 공급 업체
글로벌( 75)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32715 | 60 |
| career henan chemical co | +86-0371-86658258 15093356674; |
sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10523 | 58 |
| CD Chemical Group Limited | +8615986615575 |
info@codchem.com | China | 20356 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20391 | 58 |
| Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131980 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | |
sales@boylechem.com | China | 2923 | 55 |