KARAKOLINE

KARAKOLINE C화학적 특성, 용도, 생산

개요

A second atisine base found in the tubers of Aconitum karacolicum, the structure has been elucidated from chemical and spectroscopic data. Oxidation with KMn04 gives anhydroepoxykaracoline. The alkaloid furnishes a triacetyl deriva_x0002_tive which, after pyrolysis and hydrolysis, yields acetyldemethylisopyrokaracoline.

용도

Karacoline is an Aconitane (A189875) derivative, which is a neurotoxin which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction.

정의

ChEBI: An organonitrogen heterocyclic compound that is aconitane bearing hydroxy groups at the 1alpha, 8, and 14alpha positions and substituted at on the nitrogen and at positions 4 and 16beta by ethyl, methyl, a d methoxy groups, respectively.

참고 문헌

Sultankhodzhaev, Yunusov, Yunusov., Khim. Prir. Soedin., 9, 199 (1973)

KARAKOLINE 준비 용품 및 원자재

원자재

준비 용품

KARAKOLINE 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	sales@pioneerbiotech.com	China	3000	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8349	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10326	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58

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