1-도코사놀
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1-도코사놀 속성
- 녹는점
- 65-72 °C(lit.)
- 끓는 점
- 180 °C0.22 mm Hg(lit.)
- 밀도
- d75 0.8063 g/ml; d85 0.7986 g/ml; d95 0.7911 g/ml
- 증기압
- 0Pa at 25℃
- 굴절률
- n75 1.4360
- 저장 조건
- Store below +30°C.
- 용해도
- 클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨)
- 산도 계수 (pKa)
- 15.20±0.10(Predicted)
- 물리적 상태
- 펠릿 또는 정제
- 색상
- 하얀색
- 수용성
- 불용성
- Merck
- 13,3433
- BRN
- 1770470
- 안정성
- 안정적인. 타기 쉬운. 강한 산화제와 호환되지 않습니다.
- LogP
- 8.3 at 20℃
- CAS 데이터베이스
- 661-19-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 안전지침서 | 24/25 | ||
|---|---|---|---|
| WGK 독일 | - | ||
| RTECS 번호 | JR1315000 | ||
| TSCA | Yes | ||
| HS 번호 | 29051900 | ||
| 유해 물질 데이터 | 661-19-8(Hazardous Substances Data) | ||
| 독성 | LD50 intraperitoneal in mouse: > 800mg/kg | ||
| 기존화학 물질 | KE-12789 |
1-도코사놀 C화학적 특성, 용도, 생산
화학적 성질
1-DOCOSANOL is white powder용도
n-Docosanol is a binder and an emulsion stabilizer. It is also used to increase a formulation’s viscosity. This is a mixture of fatty alcohols. behenyl alcohol may be used for any number of purposes in a cosmetic formulation, including as an emollient, a binder, an emulsion stabilizer, or to increase a product’s viscosity. It may be derived either synthetically or from plants.정의
1-DOCOSANOL is a long-chain, saturated fatty alcohol.Indications
Docosanol (Abreva) is a long-chain saturated alcohol that is clinically effective against HSV. It has in vitro activity against many enveloped viruses, including CMV, influenzavirus, and respiratory syncytial virus.Docosanol is not directly virucidal; instead, it blocks the entry of the virion into the host cell by inhibiting the fusion of the viral envelope with the host plasma membrane. Because it does not affect viral replication or protein production, it may be less susceptible to the development of resistance than other antiviral drugs.
일반 설명
1-Docosanol inhibits replication of certain viruses (herpes simplex virus and respiratory syncytial virus) within primary target cells in vitro. It has been isolated from Clematis brevicaudata.Pharmaceutical Applications
1-DOCOSANOL is a 22-carbon straight chain alcohol licensed for over-thecounter sales for the topical treatment of herpes labialis. It is thought to act by blocking viral fusion with the host cell, although definitive studies are lacking. The clinical relevance of the antiviral activity has been debated and the place of this medication as a treatment of herpes labialis remains to be established.Clinical Use
Docosanol cream is approved for the over-the-counter treatment of herpes labialis. It shortens the duration of symptoms of cold sores and fever blisters but does not provide symptomatic relief.부작용
Adverse effects of docosanol are minimal. Skin irritation occurs infrequently. Drug interactions are not anticipated.Purification Methods
Crystallise docosanol from ether or chloroform/ether. [Beilstein 1 IV 1906.]1-도코사놀 준비 용품 및 원자재
원자재
준비 용품
1-도코사놀 공급 업체
글로벌( 389)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shandong Dexiang International Trade Co., Ltd | 15662695772;+8615662691337 |
sales006@dexiangchemical.com | China | 998 | 58 |
| Hebei Yime New Material Technology Co., Ltd. | +86-66697723 +86-17703311139 |
admin@china-yime.com | China | 563 | 58 |
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 |
Sara@xmwonderfulbio.com | China | 305 | 58 |
| Hebei Saisier Technology Co., LTD | +86-18400010335 +86-13102810335 |
admin@hbsaisier.cn | China | 852 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15932 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2989 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |