NSC63925

NSC63925 구조식 이미지
카스 번호:
20261-85-2
상품명:
NSC63925
동의어(영문):
NSC63925;AKD 1C, S 3466A;5,23-Didemethyl-5,23-diethylnonactin;4,13,22,31,37,38,39,40-Octaoxapentacyclo[32.2.1.17,10.116,19.125,28]tetracontane-3,12,21,30-tetrone, 5,23-diethyl-2,11,14,20,29,32-hexamethyl-, (1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-
CBNumber:
CB71251059
분자식:
C42H68O12
포뮬러 무게:
764.98
MOL 파일:
20261-85-2.mol

NSC63925 속성

저장 조건
Store at -20°C
용해도
DMSO에 용해됨
물리적 상태
막의

안전

NSC63925 C화학적 특성, 용도, 생산

개요

Dinactin is a macrotetrolide antibiotic that acts as an ionophore for monovalent cations, such as K+, NH4+, and Rb+. It is commonly used to study membrane properties. Dinactin is a component of a macrotetralide-rich antifungal mixture produced by Streptomyces. Dinactin inhibits T-cell proliferation and cytokine production in vitro and reduces pulmonary eosinophilia in antigen-challenged mice.

용도

Dinactin is a member of the macrotetrolide complex produced by a range of Streptomyces species. It is a monovalent cation ionophore with high selectivity for ammonium and potassium. Dinactin inhibits T-cell proliferation induced by IL-2 and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and interferon-γ. Dinactin has not previously been available for intensive investigation.

NSC63925 준비 용품 및 원자재

원자재

준비 용품


NSC63925 공급 업체

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