게미글립틴

게미글립틴
게미글립틴 구조식 이미지
카스 번호:
911637-19-9
한글명:
게미글립틴
동의어(한글):
게미글립틴
상품명:
GeMigliptin
동의어(영문):
LC15-0444;GeMigliptin;GeMigliptin WS;Gemigliptin - G10587;GeMigliptin Tartarate;Gemigliptin Hydrochloride;Product name:-Gemigliptintartarate;Inhibitor,DPP,Gemigliptin,Dipeptidyl Peptidase,inhibit;(S)-1-(2-Amino-4-(2,4-bis(trifluoromethyl)-5,6-dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-4-oxobutyl)-5,5-difluoropiperidin-2-one;1-[(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoropiperidin-2-one
CBNumber:
CB82627898
분자식:
C18H19F8N5O2
포뮬러 무게:
489.36
MOL 파일:
911637-19-9.mol

게미글립틴 속성

끓는 점
539.1±50.0 °C(Predicted)
밀도
1.54±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO:74.0(Max Conc. mg/mL);151.21(Max Conc. mM)
Ethanol:7.0(Max Conc. mg/mL);14.3(Max Conc. mM)
Water:12.0(Max Conc. mg/mL);24.52(Max Conc. mM)
산도 계수 (pKa)
7.33±0.10(Predicted)

안전

게미글립틴 C화학적 특성, 용도, 생산

개요

Gemigliptin is a prolyl-specific dipeptidyl aminopeptidase IV (DPP IV, DPP-4, CD26) inhibitor approved for the treatment of type 2 diabetes mellitus by the Korean Food and Drug Administration in 2012. Gemigliptin was discovered and developed by LG Life Sciences and is now the sixth DPP-4 inhibitor approved for the treatment of type 2 diabetes. At the time this review was prepared, there were no publications describing the discovery strategy and preclinical data that led to the advancement of gemigliptin to the clinic.

용도

Gemigliptin Hydrochloride is used in biological studies as a novel dipeptidyl peptidase IV (DPP-IV) inhibitors and potential antidiabetic drug.

게미글립틴 준비 용품 및 원자재

원자재

준비 용품


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Henan Tianfu Chemical Co.,Ltd.
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Anqing Chico Pharmaceutical Co., Ltd.
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TargetMol Chemicals Inc.
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Aceschem Inc.
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masar@topule.com China 8474 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43348 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501
product@acmec-e.com China 33350 58

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