아미그달린

아미그달린 속성

아미그달린 MSDS

(R)-Laenitrile

아미그달린 C화학적 특성, 용도, 생산

개요

Laetrile는 과일과 채소, 특히 살구 구덩이와 쓴 아몬드에서 자연적으로 발견되는 화합물 아밀돌린의 정제 된 형태입니다. Amygdalin은 1830 년에 처음으로 분리되었고 러시아에서 항암제로 일찍 사용되었습니다. laetrile는 암의 통증을 완화시킵니다. 한 가지 이론은 암 세포가 다량의 효소 베타 - 글루코시다 아제를 포함한다는 것입니다. 이 효소는 편도체를 분해하여 암 세포를 죽이는 독성 화학 물질 인 시안화를 방출합니다.

용도

1. 은 호흡기, 기침 및 천식을 억제 할 수 있습니다.
2. 분말은 항 염증 및 진통 효과를 나타냅니다.
3. 은 항 종양 효과를 나타냅니다.
4. 혈당, 저지방 혈증을 낮출 수 있습니다.
 

개요

Amygdalin is a cyanogenic glycoside that has been found in seeds from plants of the Rosaceae family and has diverse biological activities. It induces cell cycle arrest at the G₀/G₁ phase, decreases cyclin A and Cdk2 levels, and inhibits cell growth in UMUC-3, RT112, and TCCSUP bladder cancer cells when used at concentrations ranging from 1.25 to 10 mg/ml. Amygdalin (3 mg/kg) reduces the number of primary microtubules and microvessels in aortic rings isolated from rats with diabetes induced by streptozotocin . In vivo, amygdalin reduces triglyceride, total cholesterol, and LDL levels and aortic sinus plaque area in an LDLR^-/- mouse model of atherosclerosis. It also reduces production of TNF-α, IL-1β, and IL-6, as well as neutrophil and macrophage infiltration, in bronchoalveolar lavage fluid (BALF) in a mouse model of LPS-induced acute lung injury.

화학적 성질

WHITE FINE CRYSTALLINE POWDER

용도

Amygdalin, a cyanide containing glycoside, may be used as a substrate to identify, differentiate and characterize enzymes such as maltase(s), emulsin(s) and β-glucosidase(s).

정의

ChEBI: An amygdalin in which the stereocentre on the cyanohydrin function has R-configuration.

World Health Organization (WHO)

Laetrile, which consists mainly of amydgalin, a glycoside extracted from the kernels of apricots, peaches and other fruits, has been available for over 30 years in preparations purporting to be beneficial in the treatment of cancer. Although there is no evidence that these are efficacious, preparations continued to be widely used and, until the late 1970s, they were considered to be harmless. However, oral dosage forms, which may be broken down in the gut to hydrogen cyanide, have subsequently been shown to be potentially lethal. This has resulted in restrictive regulatory measures in several countries.

일반 설명

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Safety Profile

Human poison by ingestion(infant data). Poison experimentally by ingestion. Anexperimental teratogen. Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.

Purification Methods

D-Amygdalin recrystallises from water as the trihydrate, or from EtOH. It is present in bitter almonds. [Smith Chem Ber 64 1115 1931, Beilstein 17/8 V 188.]

아미그달린 준비 용품 및 원자재

원자재

준비 용품

아미그달린 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Changsha Staherb Natural Ingredients Co., Ltd.	+86-0731-84213302 +8618374838656	sales@staherb.cn	China	1025	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12467	58
Henan Tengmao Chemical Technology Co. LTD	+8615238638457	salesvip2@hntmhg.com	China	415	58
Guangzhou Tengyue Chemical Co., Ltd.	+86-86-18148706580 +8618826483838	evan@tyvovo.com	China	153	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	3001	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	1178	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9341	55
Rixing Chemical CO.,LTD	+86-13237129059 -13237129059	sales@rixingchemi.com	CHINA	229	55
Hubei XinRunde Chemical Co., Ltd.	+8615102730682	bruce@xrdchem.cn	CHINA	566	55

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