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ALDOSTERONE

ALDOSTERONE 구조식 이미지

카스 번호:: 52-39-1

상품명:: ALDOSTERONE

동의어(영문):: Reichstein;LECTROCORTIN;REICHSTEIN X;μ100 97% (CP);ALD ELISA;NSC 73856;Aldocorten;Aldocortin

CBNumber:: CB8431679

분자식:: C21H28O5

포뮬러 무게:: 360.45

MOL 파일:: 52-39-1.mol

속성

안전

용도

공급 업체 173

ALDOSTERONE 속성

녹는점: 170-172°C

알파: D23 +152.2° (anhydr; c = 2 in acetone); D25 +161° (c = 0.1 in chloroform)

끓는 점: 412.46°C (rough estimate)

밀도: 1.28

굴절률: 1.6120 (estimate)

인화점: 2℃

저장 조건: Sealed in dry,Room Temperature

용해도: 아세톤(약간 용해됨), 클로로포름(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨)

산도 계수 (pKa): 12.98±0.10(Predicted)

물리적 상태: 결정성 분말

색상: 하얀색

수용성: 51.18mg/L(37℃)

Merck: 13,224

BRN: 3224996

CAS 데이터베이스: 52-39-1(CAS DataBase Reference)

EPA: Aldosterone (52-39-1)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	Xi,Xn,F
위험 카페고리 넘버	36/37/38-36-20/21/22-11
안전지침서	22-24/25-36-26-36/37-16
유엔번호(UN No.)	UN 1648 3 / PGII
WGK 독일	3
RTECS 번호	TU4523000
F 고인화성물질	22-24-25
HS 번호	29372900

그림문자(GHS):

신호 어:

Danger

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H225	고인화성 액체 및 증기	인화성 액체	구분 2	위험		P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319	눈에 심한 자극을 일으킴	심한 눈 손상 또는 자극성 물질	구분 2A	경고		P264, P280, P305+P351+P338,P337+P313P

예방조치문구:

P210	열·스파크·화염·고열로부터 멀리하시오 - 금연 하시오.
P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

NFPA 704

	1
1		1

ALDOSTERONE C화학적 특성, 용도, 생산

개요

Aldosterone is a mineralocorticosteroid that takes part in the regulation of electrolytic balance in the organism. Aldosterone lowers excretion of sodium ions from the body, thus increasing their reabsorption and increasing secretion of potassium ions in renal tubules. Being a competitive antagonist of aldosterone, spironlactone blocks aldosterone receptors, thus increasing excretion of sodium, chloride, and corresponding equivalents of water with urine, thus retaining the amount of potassium ions in the organism. Spironolactone is used both individually as well as in combination with thiazides, since it lowers kaliuresis caused by thiazide diuretics.

화학적 성질

White Solid

용도

Labelled Aldosterone. Aldosterone is an adrenocortical steroid which exerts regulatory influence on metabolism of electrolytes and water. Biologically active aldosterone isomer; a mineralocorticoid pr oduced by the adrenal cortex that induces urinary excretion of K+ and renal reabsorptioon of Na+. Exists as an equilibrium mixture of the aldehyde and the hemiacetal.

정의

ChEBI: A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, i creased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.

건강위험

Aldosterone(Aldocortin; electrocortin; mineralocorticoid; 18-oxocorticosterone): (1)Maintenance of normal electrolyte blood balances;(2)Prolongs survival of adrenalectomized animals;(3)Accelerates gluconeogenesis;(4)Regulates kidney function.

Purification Methods

Crystallise aldosterone from aqueous acetone. It exists in solution as an equilibrium mixture of free aldehyde and its cyclic hemiacetal, favouring the hemiacetal. The 21-acetate crystallises from Me2CO/Et2O or CH2Cl2/EtOAc and has m 198-199o, [] D +121.7o (c 0.7, CHCl3). [Barton et al. J Chem Soc Perkin Trans 1 2243 1975, Beilstein 8 IV 3491.]

ALDOSTERONE 준비 용품 및 원자재

원자재

Sodium triacetoxyborohydride D-ALDOSTERONE 21-ACETATE Pregn-4-en-18-oic acid, 11,21-dihydroxy-3,20-dioxo-, γ-lactone, (11β)- (9CI) Pregn-4-en-18-oic acid, 21-(acetyloxy)-11-hydroxy-3,20-dioxo-, γ-lactone, (11β)- (9CI) Pregn-5-en-18-oic acid, 3,3:20,20-bis[1,2-ethanediylbis(oxy)]-11,21-dihydroxy-, γ-lactone, (11β)- (9CI)

준비 용품

CORTICOSTERONE

ALDOSTERONE 공급 업체

글로벌( 173)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Henan Tengmao Chemical Technology Co. LTD	+8615238638457	salesvip2@hntmhg.com	China	415	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10326	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
HONG KONG IPURE BIOLOGY CO.,LIMITED	86 18062405514 18062405514	ada@ipurechemical.com	CHINA	3465	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58

ALDOSTERONE 관련 검색:

D-ALDOSTERONE 21-ACETATE,ALDOSTERONE 21-ACETATE D-ALDOSTERONE 18,21-DIACETATE ALDOSTERONE 3-CMO : BSA ALDOSTERONE SECRETION INHIBITING FACTOR (1-35) (BOVINE) Aldosterone ELISA ALDOSTERONE, D-[1,2-3H(N)]-,[1,2-3H]ALDOSTERONE ANTI-ALDOSTERONE-3 ALDOSTERONE LABELING POSITION:3 ALDOSTERONE 3-CMO : HISTAMINE ALDOSTERONE SODIUM SULPHATE [1,2,6,7-3H]ALDOSTERONE,ALDOSTERONE, [1,2,6,7-3H]-,ALDOSTERONE, D [1,2,6,7-3H(N)] ALDOSTERONE 18,21-DIACETATE ALDOSTERONE GAMMA LACTONE Aldosterone, bis(O-trimethylsilyl-) D-ALDOSTERONE 21-HEMISUCCINATE*CRYSTALLINE ALDOSTERONE-3-BSA,RABBITANTI-:RIA ALDOSTERONE ANTI- KV FOR 3H MAb to Aldosterone Purified (1)