2,2-diphenyl-1-picrylhydrazyl

2,2-diphenyl-1-picrylhydrazyl 구조식 이미지
카스 번호:
1898-66-4
상품명:
2,2-diphenyl-1-picrylhydrazyl
동의어(영문):
DPPH;1,1-DIPHENYL-2-PICRYLHYDRAZYL;1,1-Diphenyl-2-picrylhydrazyl radical;2,2-Diphenylpicrylhydrazyl;2,2-Diphenyl-1-picrylhydrazyl radical(DPPH);hydrazyL;-1-picryL;Diphenypicrylhydrazyl;inhibit,DPPH,Inhibitor;Diphenylpicrylhydrazyl.
CBNumber:
CB8753025
분자식:
C18H12N5O6*
포뮬러 무게:
394.32
MOL 파일:
1898-66-4.mol
MSDS 파일:
SDS

2,2-diphenyl-1-picrylhydrazyl 속성

녹는점
~135 °C (dec.)(lit.)
밀도
1.484 g/cm3
저장 조건
2-8°C
용해도
아세토니트릴(약간 용해됨), 클로로포름(약간 용해됨), DMSO(약간 용해됨)
물리적 상태
고체
물리적 상태
단단한 모양
색상
녹색
수용성
디메틸 포름아미드, 에탄올, 클로로포름, 에테르, 이황화탄소, 아세톤, 오일, 사염화탄소, 빙초산 및 톨루엔에 용해됩니다. 물에 불용성.
최대 파장(λmax)
515nm(MeOH)(lit.)
Merck
14,3330
BRN
1846081
안정성
충격에 민감함
EPA
Hydrazyl, 2,2-diphenyl-1-(2,4,6-trinitrophenyl)- (1898-66-4)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn
위험 카페고리 넘버 42/43
안전지침서 22-36/37-45
유엔번호(UN No.) UN2811
WGK 독일 1
RTECS 번호 MW3250000
TSCA Yes
위험 등급 6.1
포장분류 II
HS 번호 29280000
그림문자(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H242 가열하면 화재를 일으킬 수 있음 자기반응성 물질 및 혼합물;유기과산화물 형식 C, D,형식 E, F
형식 G
위험
경고
GHS hazard pictograms P210, P220, P234, P280, P370+P378,P403+P235, P411, P420, P501
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 알레르기성 피부 반응을 일으킬 수 있음 피부 과민성 물질 구분 1 경고 GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H334 흡입 시 알레르기성 반응, 천식 또는 호흡 곤란 등을 일으킬 수 있음 호흡기 과민성 물질 구분 1 위험 GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
예방조치문구:
P210 열·스파크·화염·고열로부터 멀리하시오 - 금연 하시오.
P235 저온으로 유지하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P370+P378 화재 시 불을 끄기 위해 (Section 5. 폭발, 화재시 대처방법의 적절한 소화제)을(를) 사용하시오.
P403 환기가 잘 되는 곳에 보관하시오.
NFPA 704
0
2 0

2,2-diphenyl-1-picrylhydrazyl C화학적 특성, 용도, 생산

화학적 성질

DPPH is a common abbreviation for the organic chemical compound 2,2-diphenyl-1-picrylhydrazyl. It is a dark-colored crystalline powder composed of stable free radical molecules. DPPH has two major applications, both in laboratory research: one is a monitor of chemical reactions involving radicals, most notably it is a common antioxidant assay, and another is a standard of the position and intensity of electron paramagnetic resonance signals.

물리적 성질

DPPH has several crystalline forms which differ by the lattice symmetry and melting point. The commercial powder is a mixture of phases which melts at ~130 °C. DPPH-I (m.p. 106 °C) is orthorhombic, DPPH-II (m.p. 137 °C) is amorphous and DPPH-III (m.p. 128–129 °C) is triclinic.

일반 설명

2,2-diphenyl-1-picrylhydrazyl is a free radical, which shows hydrogen acceptor ability towards antioxidants. It has a strong absorbance at 517 nm. When the radical is lost in exchange for a proton, the absorbance at 517 nm decreases proportionately, resulting in a color change from purple to yellow. Hence, it is commonly used in DPPH assay for measuring the antioxidant activity of different natural samples such as wine, fruits, herbal tea etc.

Safety

This picrylhydrazyl derivative, also known as DPPH free radical, presents as a black crystalline powder. Store in a refrigerator - this substance is heat sensitive. 1,1-Diphenyl-2-picrylhydrazyl Free Radical is incompatible with oxidizing agents, strong bases and halogens. This chemical is harmful if swallowed. It may cause allergy or asthma symptoms or breathing difficulties if inhaled and an allergic reaction on the skin.

참고 문헌

[1] SIDDARTHA BALIYAN. Determination of Antioxidants by DPPH Radical Scavenging Activity and Quantitative Phytochemical Analysis of Ficus religiosa.[J]. Molecules, 2022. DOI:10.3390/molecules27041326.
[2] G. CLARKE. High Correlation of 2,2-diphenyl-1-picrylhydrazyl (DPPH) Radical Scavenging, Ferric Reducing Activity Potential and Total Phenolics Content Indicates Redundancy in Use of All Three Assays to Screen for Antioxidant Activity of Extracts of Plants from the Malaysian Rainforest[C]//2 1. 2013: 1-10. DOI:10.3390/antiox2010001.
[3] IKUO NAKANISHI Yoshimi S. Electrochemical redox behavior of 2,2-diphenyl-1-picrylhydrazyl radical solubilized by β-cyclodextrin in water[J]. Electrochemistry Communications, 2022, 134: Article 107190. DOI:10.1016/j.elecom.2021.107190.
[4] JAMES BYH BEHRENDORFF. 2,2-Diphenyl-1-picrylhydrazyl as a screening tool for recombinant monoterpene biosynthesis.[J]. Microbial Cell Factories, 2013, 12: 76. DOI:10.1186/1475-2859-12-76.
[5] J. XIE K. M S. Re-evaluation of the 2,2-Diphenyl-1-picrylhydrazyl Free Radical (DPPH) Assay for Antioxidant Activity[J]. Journal of Agricultural and Food Chemistry, 2014, 62 19: 4251-4260. DOI:10.1021/jf500180u.

2,2-diphenyl-1-picrylhydrazyl 준비 용품 및 원자재

원자재

준비 용품


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