QUERCETINPENTAACETATE

QUERCETINPENTAACETATE 구조식 이미지
카스 번호:
1064-06-8
상품명:
QUERCETINPENTAACETATE
동의어(영문):
Quercetin acetate;Pentaacetylquercetin;Quercetine pentaacetate;3,3',4',5,7-Pentaacetoxyflavone;3,3',4',5,7-Penta(acetyloxy)flavone;3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one;2-(3,4-diacetoxyphenyl)-4-oxo-4H-chromene-3,5,7-triyl triacetate;[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate;Quercetin pentaacetate,Respiratory syncytial virus,inhibit,Inhibitor,RSV;4H-1-Benzopyran-4-one, 3,5,7-tris(acetyloxy)-2-[3,4-bis(acetyloxy)phenyl]-
CBNumber:
CB91405559
분자식:
C25H20O12
포뮬러 무게:
512.42
MOL 파일:
1064-06-8.mol

QUERCETINPENTAACETATE 속성

녹는점
193 °C
끓는 점
666.4±55.0 °C(Predicted)
밀도
1.45±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
디클로로메탄, 에틸아세테이트에용해됨
물리적 상태
고체
물리적 상태
단단한 모양
색상
베이지색

안전

QUERCETINPENTAACETATE C화학적 특성, 용도, 생산

개요

Pentaacetylquercetin is a pentaacetylated derivative of the flavonoid quercetin that has diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in vitro (IC50 = 3.74 μg/ml) and inhibits iron(II) chloride-induced lipid peroxidation in rat liver mitochondria (IC50 = 20.2 μg/ml). Pentaacetylquercetin inhibits LPS-induced increases in nitrite (IC50 = 8.7 μM) and PGE2 production, as well as inducible nitric oxide synthase (iNOS) and COX-2 levels, in RAW 264.7 cells when used at concentrations of 20 and 40 μM. It also inhibits the growth of HL-60, U937, and SK-MEL-1 cells (IC50s = 38, 25, and 58 μM, respectively).

용도

[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.

QUERCETINPENTAACETATE 준비 용품 및 원자재

원자재

준비 용품


QUERCETINPENTAACETATE 공급 업체

글로벌( 19)공급 업체
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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TargetMol Chemicals Inc.
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Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720
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Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11289 58
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44894 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223
psaitong@jm-bio.com China 29834 58
Beijing Stronger Science Co., Ltd. 0531-88924771 15614660963
elsa.hang@strongerscience.com China 10624 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24131 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 8740 58

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