8-M-PDOT
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8-M-PDOT 속성
- 끓는 점
- 447.8±45.0 °C(Predicted)
- 밀도
- 1.09±0.1 g/cm3(Predicted)
- 저장 조건
- Store at RT
- 용해도
- Soluble to 50 mM in ethanol and to 100 mM in DMSO
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 15.87±0.20(Predicted)
안전
8-M-PDOT C화학적 특성, 용도, 생산
개요
8-M-PDOT is a melatonin receptor 2 (MT2) agonist (Ki = 1.12 nM). It is 5.2-fold selective for MT2 over MT1 receptors in a radioligand binding assay. Striatal microinfusion of 8-M-PDOT (10 μg/μl) increases the percentage of time spent in the open arms of the elevated plus maze, indicating anxiolytic-like activity, in a rat model of rotenone-induced Parkinson''s disease.생물학적 활성
Melatonin receptor agonist, 20-fold selective for the MT 2 (vs MT 1 ) subtype. At human recombinant MT 1 and MT 2 receptors, displays pK i values of 8.23 and 8.95 respectively.8-M-PDOT 준비 용품 및 원자재
원자재
준비 용품
8-M-PDOT 공급 업체
글로벌( 29)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 |
info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9709 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 |
psaitong@jm-bio.com | China | 29778 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 |
gaojun@univ-bio.com | China | 24998 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 |
sales@hasunny.com | China | 2380 | 58 |
| TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24017 | 58 |