Ceftibuten manufacturers and suppliers

Ceftibuten suppliers

Properties

Boiling point:: 966℃

Density: 1.75±0.1 g/cm3(Predicted)

RTECS: XI0367220

Flash point:: >110°(230°F)

storage temp.: Keep in dark place,Sealed in dry,2-8°C

solubility: Soluble in aqueous solutions. Also soluble in DMSO

form: powder

pka: 2.99±0.50(Predicted)

color: white to beige

Safety Information

Symbol(GHS): GHS07,GHS08

Signal word: Danger

Hazard statements: H332-H334

Precautionary statements: P261-P271-P304+P340-P312-P261-P285-P304+P341-P342+P311-P501

WGK Germany: 3

Use

Ceftibuten (Cedax) is a recently introduced, chemicallynovel analog of the oximino cephalosporins in which anolefinic methylene group (C＝CHCH2-) with Z stereochemistryhas replaced the syn oximino (CBNO-) group.This isosteric replacement yields a compound that retainsresistance to hydrolysis catalyzed by many β-lactamases,has enhanced chemical stability, and is orally active. Oralabsorption is rapid and nearly complete. It has the highestoral bioavailability of the third-generation cephalosporins.Ceftibuten is excreted largely unchanged in the urine andhas a half-life of about 2.5 hours. Plasma protein binding ofthis cephalosporin is estimated to be 63%.Ceftibuten possesses excellent potency against mostmembers of the Enterobacteriaceae family, H. influenzae,Neisseria spp., and M. catarrhalis. It is not active against S.aureus or P. aeruginosa and exhibits modest antistreptococcal activity. Ceftibuten is recommended in the managementof community-acquired respiratory tract, urinary tract, andgynecological infections.

You can find Ceftibuten suppliers, manufacturers, and distributors from countries such as CHINA, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.