Ambrisentan manufacturers and suppliers

Ambrisentan suppliers

Properties

Melting point:: >150°C (dec.)

Boiling point:: 551.1±60.0 °C(Predicted)

Density: 1.228±0.06 g/cm3(Predicted)

storage temp.: Sealed in dry,2-8°C

solubility: DMSO (Slightly), Methanol (Slightly)

form: Solid

pka: 0.97±0.10(Predicted)

color: White to Off-White

Merck: 14,384

Safety Information

Symbol(GHS): GHS08

Signal word: Danger

Hazard statements: H360FD

Precautionary statements: P201-P308+P313

Risk Statements: 62/63

Safety Statements: 53-36/37/39-45

RTECS: UA2459660

HS Code: 29335990

Use

Ambrisentan, (+)-(2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid(Letairis), is a potent ETA selective endothelin antagonist that,is indicated, in the treatment of pulmonary arterial hypertension(PAH). PAH is a rare disease that if left untreated has ahigh mortality rate. In June of 2007, the FDA granted approvalof ambrisentan for once-daily treatment of PAH.Studies have shown that it improves a 6-minute walk by about30 to 60 m for patients receiving placebo.

You can find Ambrisentan suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.