Arteether manufacturers and suppliers

Arteether suppliers

Properties

Melting point:: 80-820C

alpha: D21 +154.5° (c = 1.0 in CHCl3)

Boiling point:: 372.4±42.0 °C(Predicted)

Density: 1.16±0.1 g/cm3(Predicted)

storage temp.: Sealed in dry,2-8°C

solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)

form: Solid

color: White

Safety Information

Symbol(GHS): GHS06,GHS02

Signal word: Danger

Hazard statements: H301+H311+H331-H226

Precautionary statements: P501-P261-P270-P240-P210-P233-P243-P241-P242-P271-P264-P280-P370+P378-P361+P364-P303+P361+P353-P301+P310+P330-P304+P340+P311-P403+P233-P403+P235-P405

Use

Arteether reached the market in the Netherlands as a solution in sesame oil, administered by i.m. injection, for the treatment of severe malaria infections in children and adolescents. Artheether, a sesquiterpene acetal with an endoperoxide bridge, is an ether derivative of the naturally occuring compound artemisinin, the active component of Chinese herbal remedies. As the other structural analogs of artemisinin, such as artesunate or artemether, it acts rapidly against Plasmodium, the parasite responsible for the disease, during the early blood stage of its development. It also exhibits a gametocytocidal activity against Plasmodium falciparum, reducing its potential for transmission. Because the only controlled clinical studies had been performed in children and adolescents, this new antimalarial drug was only approved for young patients. Further studies in adults treated with 150 mg i.m. artemotil, once daily for three consecutive days, indicated that the drug was efficient, rapidly acting (parasite clearance time meanly 38 h) and well tolerated. A new promising achievement in the regression of malaria is the combination of artemisinin derivatives with other long-lived antimalarials as mefloquine or pyrimethamine/sulfa.

You can find Arteether suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.