Clofazimine manufacturers and suppliers

Clofazimine suppliers

Properties

Melting point:: 210-212°

Boiling point:: 616.26°C (rough estimate)

Density: 1.1342 (rough estimate)

refractive index: 1.6300 (estimate)

storage temp.: 2-8°C

solubility: Practically insoluble in water, soluble in methylene chloride, very slightly soluble in ethanol (96 per cent). It shows polymorphism (5.9).

pka: 8.37; also reported as 8.51(at 25℃)

color: Yellow to Amber to Dark red

Water Solubility: 10mg/L(temperature not stated)

Merck: 14,2373

BCS Class: 4/3

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H335-H319-H413

Precautionary statements: P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

Hazard Codes: Xn,Xi

Risk Statements: 22-36/37/38

Safety Statements: 36-26

WGK Germany: 3

RTECS: SG1578000

HS Code: 35040000

Toxicity: LD50 orally in mice, rats, and guinea pigs: >4 g/kg (Stenger)

Use

Clofazimine (Lamprene) is a basic red dye that exerts a slow bactericidal effect on M. leprae, the bacterium that causes leprosy. It occurs as a dark red crystalline solid that is insoluble in water. Clofazimine is used in the treatment of lepromatous leprosy, including dapsone-resistant forms of the disease. In addition to its antibacterial action, the drug appears to possess anti-inflammatory and immune-modulating effects that are of value in controlling neuritic complications and in suppressing erythema nodosum leprosum reactions associated with lepromatous leprosy. It is frequently used in combination with other drugs, such as dapsone or rifampin.

You can find Clofazimine suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.