Pimavanserin suppliers
Pimavanserin
- CAS:
- 706779-91-1
- MF:
- C25H34FN3O2
- MW:
- 427.55
Suppliers by country/region
Company Type
Properties
- Melting point:
- 100-103oC
- Boiling point:
- 604.2±55.0 °C(Predicted)
- Density
- 1.15±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Methanol (Slightly)
- pka
- 13.52±0.46(Predicted)
- form
- Solid
- color
- Pale Yellow to Pale Orange
- InChI
- InChI=1S/C25H34FN3O2/c1-19(2)18-31-24-10-6-20(7-11-24)16-27-25(30)29(23-12-14-28(3)15-13-23)17-21-4-8-22(26)9-5-21/h4-11,19,23H,12-18H2,1-3H3,(H,27,30)
- InChIKey
- RKEWSXXUOLRFBX-UHFFFAOYSA-N
- SMILES
- N(CC1=CC=C(F)C=C1)(C1CCN(C)CC1)C(NCC1=CC=C(OCC(C)C)C=C1)=O
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
- Hazard Codes
- Xi
- Safety Statements
- 24/25
- HS Code
- 29339900
Use
Pimavanserin is an atypical antipsychotic which is approved for the treatment of Parkinson's disease psychosis and is also being researched for the treatment of Alzheimer’s disease psychosis, schizophrenia, agitation, and major depressive disorder. Unlike other antipsychotics, pimavanserin is not a dopamine receptor antagonist. Pimavanserin acts as an inverse agonist and antagonist at serotonin 5-HT2A [5] receptors with high binding affinity (Ki 0.087 nM) and at serotonin 5-HT2C receptors with lower binding affinity (Ki 0.44 nM). Pimavanserin shows low binding to σ1 receptors (Ki 120 nM) and has no appreciable affinity (Ki >300 nM) to serotonin 5-HT2B, dopamine (including D2), muscarinic acetylcholine, histamine, or adrenergic receptors, or to calcium channels.
177 supplier list of "Pimavanserin"
$0.00-0.00 / 1kg
- Product Name:Pimavanserin
- Products Intro:Purity: 99% | Package: 1KG.5KG;25KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Upadacitinib,Vonoprazan Fumarate,Cyanocobalamin,Tofacitinib citrate,vitamins
$650.00-350.00 / 1Kg/Bag
- Product Name:Pimavanserin
- Products Intro:Purity: 99% up, High Density|Package: 1Kg/Bag;650.00;USD|25Kg/Bag;550.00;USD|100Kg/Bag;350.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: APIs,pharmaceutical intermediates,health and food supplements,cosmetic raw materials,herbal extracts
$0.00/ 1g
- Product Name:Pimavanserin
- Products Intro:Purity: 98% HPLC | Package: 1g
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Inosine pranobex,Probenecid,Sodium Ceftiofur,3-O-Ethyl-L-ascorbic acid,benzhexol hydrochloride
$35.00-0.90 / 1kg
- Product Name:Pimavanserin
- Products Intro:Purity: 99% | Package: 1kg;35USD|1000kg;0.9USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,Petrochemicals,Chemical reagents,Intermediates
$2.00/ 1kg
- Product Name:Pimavanserin
- Products Intro:Purity: 99% | Package: 1kg;2USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information