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ChemicalBook >> CAS DataBase List >> 4,4'-diacetyldiphenylureabis(guanylhydrazone)ditosylate

4,4'-diacetyldiphenylureabis(guanylhydrazone)ditosylate

4,4'-diacetyldiphenylureabis(guanylhydrazone)ditosylate price.
  • $25 - $1075
  • Product name: 4,4'-diacetyldiphenylureabis(guanylhydrazone)ditosylate
  • CAS: 15427-93-7
  • MF: C20H28N10O4S
  • MW: 504.56592
  • EINECS:
  • MDL Number:
  • Synonyms:NSC 109555;2,2′-[Carbonylbis(imino-4,1-phenyleneethylidyne)]-bis-Hydrazinecarboximidamide methanesulfonate (1:2);NSC109555 Dimesylate;4,4'-diacetyldiphenylureabis(guanylhydrazone)ditosylate;NSC 109555 ditosylate;DDUG dimethanesulfonate;DDUG diMS
11 prices
Selected condition:
Brand
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 10
  • 50mg
  • ManufacturerCayman Chemical
  • Product number19811
  • Product descriptionNSC 109555
  • Packaging1mg
  • Price$25
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19811
  • Product descriptionNSC 109555
  • Packaging5mg
  • Price$84
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19811
  • Product descriptionNSC 109555
  • Packaging10mg
  • Price$140
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19811
  • Product descriptionNSC 109555
  • Packaging50mg
  • Price$521
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number66485
  • Product descriptionNSC109555
  • Packaging50mg
  • Price$1075
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0781
  • Product descriptionNSC109555 ≥98% (HPLC)
  • Packaging5mg
  • Price$95.7
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0781
  • Product descriptionNSC109555 ≥98% (HPLC)
  • Packaging25mg
  • Price$377
  • Updated2022-05-15
  • Buy
  • ManufacturerTocris
  • Product number3034
  • Product descriptionNSC109555ditosylate ≥98%(HPLC)
  • Packaging10
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number3034
  • Product descriptionNSC109555ditosylate ≥98%(HPLC)
  • Packaging50
  • Price$794
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberN900530
  • Product descriptionNSC109555
  • Packaging10mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number256049
  • Product descriptionNSC 109555 ditosylate
  • Packaging10mg
  • Price$438
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 19811 NSC 109555 1mg $25 2024-03-01 Buy
Cayman Chemical 19811 NSC 109555 5mg $84 2024-03-01 Buy
Cayman Chemical 19811 NSC 109555 10mg $140 2024-03-01 Buy
Cayman Chemical 19811 NSC 109555 50mg $521 2024-03-01 Buy
Medical Isotopes, Inc. 66485 NSC109555 50mg $1075 2021-12-16 Buy
Sigma-Aldrich SML0781 NSC109555 ≥98% (HPLC) 5mg $95.7 2022-05-15 Buy
Sigma-Aldrich SML0781 NSC109555 ≥98% (HPLC) 25mg $377 2022-05-15 Buy
Tocris 3034 NSC109555ditosylate ≥98%(HPLC) 10 $189 2021-12-16 Buy
Tocris 3034 NSC109555ditosylate ≥98%(HPLC) 50 $794 2021-12-16 Buy
TRC N900530 NSC109555 10mg $135 2021-12-16 Buy
Usbiological 256049 NSC 109555 ditosylate 10mg $438 2021-12-16 Buy

Properties

storage temp. :2-8°C
solubility :H2O: soluble5mg/mL, clear (warmed)
form :powder
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

NSC 109555 is an inhibitor of checkpoint kinase 2 (Chk2), a serine/threonine kinase involved in the ATM-Chk2 checkpoint pathway. Drugs that target Chk2 in combination with DNA-damaging agents can be beneficial in cancer therapy. Studies in mice, rats, rabbits, dogs, and monkeys have shown that NSC 109555 displays toxic effects. A singe injection of the drug at a concentration of 12.5-25 mg/kg caused acute paralysis leading to apnea and death.