Aminophylline
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- $14 - $2489.66
- Product name: Aminophylline
- CAS: 317-34-0
- MF: C9H16N6O2
- MW: 240.27
- EINECS:206-264-5
- MDL Number:MFCD00013221
- Synonyms:AMinophyllin Anhydrous USP;3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione;Aminophylline dihydrochloride hyderate;Aminophylline, >=98%;(Theophylline)2 · Ethylenediamine 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione, cmpd. with 1,2-ethanediamine (2:1) Theophylline hemiethylenediamine complex Theophylline, compound with ethylenediamine (2 to 1) dihydrate Theophylli;3,7-dihydro-1,3-dimethyl-1h-purine-2,6-dionecompd.with1,2-ethanediamine(2 ;aminocadol ;aminodur
25 prices
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Brand
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- Sigma-Aldrich
- TRC
Package
- 25MG
- 100mg
- 200mg
- 500mg
- 1g
- 5g
- 25g
- 50g
- 100g
- 250G
- 500g
- 1KG
- ManufacturerAK Scientific
- Product numberE719
- Product descriptionAminophylline
- Packaging5g
- Price$14
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number5134AF
- Product descriptionAminophyllinedihydrate
- Packaging25g
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60705
- Product descriptionAminophylline, anhydrous, 98%
- Packaging25g
- Price$31.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60705
- Product descriptionAminophylline, anhydrous, 98%
- Packaging100g
- Price$98.3
- Updated2024-03-01
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007618
- Product descriptionAMINOPHYLLINE 95.00%
- Packaging25MG
- Price$253.05
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007618
- Product descriptionAMINOPHYLLINE 95.00%
- Packaging100G
- Price$2489.66
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4346
- Product descriptionAminophylline
- Packaging200mg
- Price$92
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBA166016
- Product descriptionAminophylline
- Packaging100mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA03740
- Product descriptionAminophylline
- Packaging100g
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA03740
- Product descriptionAminophylline
- Packaging500g
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22235
- Product descriptionAminophylline ≥98%
- Packaging25g
- Price$26
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22235
- Product descriptionAminophylline ≥98%
- Packaging50g
- Price$48
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22235
- Product descriptionAminophylline ≥98%
- Packaging100g
- Price$79
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22235
- Product descriptionAminophylline ≥98%
- Packaging500g
- Price$328
- Updated2024-03-01
- Buy
- ManufacturerChem-Impex
- Product number32445
- Product descriptionAminophylline,Ethylenediamine:13.515.0%Theopyllineanhydrous:84.087.4% Ethylenediamine:13.515.0%Theopyllineanhydrous:84.087.4%
- Packaging25G
- Price$22.4
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number32445
- Product descriptionAminophylline,Ethylenediamine:13.515.0%Theopyllineanhydrous:84.087.4% Ethylenediamine:13.515.0%Theopyllineanhydrous:84.087.4%
- Packaging100G
- Price$50.4
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | E719 | Aminophylline | 5g | $14 | 2021-12-16 | Buy |
| AK Scientific | 5134AF | Aminophyllinedihydrate | 25g | $110 | 2021-12-16 | Buy |
| Alfa Aesar | J60705 | Aminophylline, anhydrous, 98% | 25g | $31.65 | 2024-03-01 | Buy |
| Alfa Aesar | J60705 | Aminophylline, anhydrous, 98% | 100g | $98.3 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | API0007618 | AMINOPHYLLINE 95.00% | 25MG | $253.05 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007618 | AMINOPHYLLINE 95.00% | 100G | $2489.66 | 2021-12-16 | Buy |
| ApexBio Technology | A4346 | Aminophylline | 200mg | $92 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BA166016 | Aminophylline | 100mg | $50 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA03740 | Aminophylline | 100g | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA03740 | Aminophylline | 500g | $250 | 2021-12-16 | Buy |
| Cayman Chemical | 22235 | Aminophylline ≥98% | 25g | $26 | 2024-03-01 | Buy |
| Cayman Chemical | 22235 | Aminophylline ≥98% | 50g | $48 | 2024-03-01 | Buy |
| Cayman Chemical | 22235 | Aminophylline ≥98% | 100g | $79 | 2024-03-01 | Buy |
| Cayman Chemical | 22235 | Aminophylline ≥98% | 500g | $328 | 2024-03-01 | Buy |
| Chem-Impex | 32445 | Aminophylline,Ethylenediamine:13.515.0%Theopyllineanhydrous:84.087.4% Ethylenediamine:13.515.0%Theopyllineanhydrous:84.087.4% | 25G | $22.4 | 2021-12-16 | Buy |
| Chem-Impex | 32445 | Aminophylline,Ethylenediamine:13.515.0%Theopyllineanhydrous:84.087.4% Ethylenediamine:13.515.0%Theopyllineanhydrous:84.087.4% | 100G | $50.4 | 2021-12-16 | Buy |
Properties
Melting point :269-270 °C
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: 3.7 mg/mL solutions should be freshly prepared.
form :powder
pka :pKa 5.0 (Uncertain)
color :white to off-white
Water Solubility :soluble
Merck :14,465
InChI :InChI=1S/C7H8N4O2.C2H8N2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;3-1-2-4/h3H,1-2H3,(H,8,9);1-4H2
InChIKey :LHRHXWBJUQKYEL-UHFFFAOYSA-N
SMILES :O=C1N(C(=O)N(C)C2NC=NC1=2)C.C(N)CN
LogP :-0.175 (est)
CAS DataBase Reference :317-34-0(CAS DataBase Reference)
EPA Substance Registry System :1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compd. with 1,2-ethanediamine (2:1) (317-34-0)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: 3.7 mg/mL solutions should be freshly prepared.
form :powder
pka :pKa 5.0 (Uncertain)
color :white to off-white
Water Solubility :soluble
Merck :14,465
InChI :InChI=1S/C7H8N4O2.C2H8N2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;3-1-2-4/h3H,1-2H3,(H,8,9);1-4H2
InChIKey :LHRHXWBJUQKYEL-UHFFFAOYSA-N
SMILES :O=C1N(C(=O)N(C)C2NC=NC1=2)C.C(N)CN
LogP :-0.175 (est)
CAS DataBase Reference :317-34-0(CAS DataBase Reference)
EPA Substance Registry System :1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compd. with 1,2-ethanediamine (2:1) (317-34-0)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Aminophylline is a drug combination consisting of bronchodilator theophylline and ethylenediamine in 2: 1 ratio. It is a kind of non-selective adenosine receptor blocker, histone deacetylase activator and phosphodiesterase inhibition. It is mainly indicated for the treatment of various kinds of lung diseases including asthma, COPD, chronic bronchitis and emphysema. Aminophylline exerts its effect through the component of theophylline in vivo. Theophylline can relax the smooth muscle of the bronchial airways and pulmonary blood vessels. It can competitively inhibits type III and type IV phosphodiesterase (PDE), which breaks down cyclic AMP in smooth muscle cells, possibly leading to bronchodilation. Theophylline also binds to the adenosine A2B receptor to block the adenosine mediated bronchoconstriction. Furthermore, during the inflammatory states, theophylline can activate the histone deacetylase to prevent transcription of inflammatory genes that require the acetylation of histones to initiate the transcription.Related product price
- 110-18-9
$10-2091.4 - Theophylline
$5-849 - 2,6-Dimethyl-7-octen-2-ol
$45-1834.57
Suppliers and manufacturers
Hubei Ipure Biology Co., Ltd
APOLLO HEALTHCARE RESOURCES
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Hubei XinRunde Chemical Co., Ltd.
