BPV(PHEN)

$73.6 - $274
Product name: BPV(PHEN)
CAS: 42494-73-5
MF: C12H8KN2O5V
MW: 350.24
EINECS:
MDL Number:MFCD32671691
Synonyms:POTASSIUM BISPEROXO(1,10-PHENANTHROLINE)OXOVANADATE (V);BPV(PHEN);K[VO(O2)2C12H8N2] 3H2O;Potassium Bisperoxo(1,10-phenanthroline)oxovanadate (V) trihydrate;bpV(phen) - CAS 42494-73-5 - Calbiochem

Price4 Properties Safety Information Description

4 prices

Selected condition：

Brand

American Custom Chemicals Corporation
Sigma-Aldrich

Package

5MG
10mg
25mg

ManufacturerAmerican Custom Chemicals Corporation
Product numberING0014935
Product descriptionbpV(phen) 95.00%
Packaging5MG
Price$233.2
Updated2021-12-16
Buy

ManufacturerSigma-Aldrich
Product numberSML0889
Product descriptionbpV(phen) ≥95% V basis
Packaging5mg
Price$73.6
Updated2024-03-01
Buy

ManufacturerSigma-Aldrich
Product number203695
Product descriptionbpV(phen)
Packaging10mg
Price$245
Updated2024-03-01
Buy

ManufacturerSigma-Aldrich
Product numberSML0889
Product descriptionbpV(phen) ≥95% V basis
Packaging25mg
Price$274
Updated2024-03-01
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	ING0014935	bpV(phen) 95.00%	5MG	$233.2	2021-12-16	Buy
Sigma-Aldrich	SML0889	bpV(phen) ≥95% V basis	5mg	$73.6	2024-03-01	Buy
Sigma-Aldrich	203695	bpV(phen)	10mg	$245	2024-03-01	Buy
Sigma-Aldrich	SML0889	bpV(phen) ≥95% V basis	25mg	$274	2024-03-01	Buy

Properties

storage temp. :-20°C
solubility :H2O: soluble20mg/mL, clear
form :Yellow solid
color :faint yellow to dark yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

bpV(phen), or potassium bisperoxo (1,10-phenanthroline) oxovanadate, is a peroxovanadium (pV) small molecule with insulin-mimetic properties. bpV(phen) and other pV compounds were demonstrated to activate insulin receptor kinase in hepatocytes and to inhibit the dephosphorylation of autophosphorylated insulin receptors, correlated to significant decreases of circulating insulin and plasma glucose levels. Inhibition of an endosomally-located protein phosphotyrosine phosphatase by bpV(phen) produces this blockade of insulin receptor dephosphorylation. bpV(phen) is also described to activate a signal pathway which abrogates dexamethasone/glucagon-induced increase of IGFBP-1 (insulin-like growth factor binding protein-1) mRNA, and this effect is suggested to be mediated through MAP kinase activity stimulated by bpV(phen) inhibition of tyrosine phosphatases involved in MAP kinase regulation.

Suppliers and manufacturers

TargetMol Chemicals Inc.

Henan Alfa Chemical Co., Ltd

Aladdin Scientific Sigma-Aldrich Beijing Jin Ming Biotechnology Co., Ltd. Beijing Jin Ming Biotechnology Co., Ltd. TargetMol Chemicals Inc. Shanghai Maclean Biochemical Technology Co., LTD

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