Debio-1347
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- $49 - $1700
- Product name: Debio-1347
- CAS: 1265229-25-1
- MF: C20H16N6O
- MW: 356.38
- EINECS:
- MDL Number:MFCD28502053
- Synonyms:Debio-1347;FF284;CH5183284 (Debio-1347);(5-amino-1-(2-methyl-3H-benzo[d]imidazol-5-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone;CH5183284;Debio-1347:CH5183284;CH5183284;CH-5183284;CH 5183284;CS-1637
20 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 1g
- 10mM(in 1mL DMSO)
- 100mg
- ManufacturerAK Scientific
- Product number2863DS
- Product descriptionDebio-1347
- Packaging25mg
- Price$626
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4985
- Product descriptionCH5183284(Debio-1347)
- Packaging5mg
- Price$103
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4985
- Product descriptionCH5183284(Debio-1347)
- Packaging10mM(in 1mL DMSO)
- Price$121
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4985
- Product descriptionCH5183284(Debio-1347)
- Packaging25mg
- Price$334
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4985
- Product descriptionCH5183284(Debio-1347)
- Packaging100mg
- Price$698
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17120
- Product descriptionCH5183284 ≥95%
- Packaging1mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17120
- Product descriptionCH5183284 ≥95%
- Packaging5mg
- Price$120
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17120
- Product descriptionCH5183284 ≥95%
- Packaging10mg
- Price$216
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17120
- Product descriptionCH5183284 ≥95%
- Packaging25mg
- Price$475
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5504
- Product descriptionCH5183284 99.73%
- Packaging5mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5504
- Product descriptionCH5183284 99.73%
- Packaging10mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5504
- Product descriptionCH5183284 99.73%
- Packaging25mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5504
- Product descriptionCH5183284 99.73%
- Packaging50mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5504
- Product descriptionCH5183284 99.73%
- Packaging100mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004042
- Product descriptionCH5183284 98+%
- Packaging10mg
- Price$216
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004042
- Product descriptionCH5183284 98+%
- Packaging25mg
- Price$443
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2863DS | Debio-1347 | 25mg | $626 | 2021-12-16 | Buy |
| ApexBio Technology | B4985 | CH5183284(Debio-1347) | 5mg | $103 | 2021-12-16 | Buy |
| ApexBio Technology | B4985 | CH5183284(Debio-1347) | 10mM(in 1mL DMSO) | $121 | 2021-12-16 | Buy |
| ApexBio Technology | B4985 | CH5183284(Debio-1347) | 25mg | $334 | 2021-12-16 | Buy |
| ApexBio Technology | B4985 | CH5183284(Debio-1347) | 100mg | $698 | 2021-12-16 | Buy |
| Cayman Chemical | 17120 | CH5183284 ≥95% | 1mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 17120 | CH5183284 ≥95% | 5mg | $120 | 2024-03-01 | Buy |
| Cayman Chemical | 17120 | CH5183284 ≥95% | 10mg | $216 | 2024-03-01 | Buy |
| Cayman Chemical | 17120 | CH5183284 ≥95% | 25mg | $475 | 2024-03-01 | Buy |
| ChemScene | CS-5504 | CH5183284 99.73% | 5mg | $55 | 2021-12-16 | Buy |
| ChemScene | CS-5504 | CH5183284 99.73% | 10mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-5504 | CH5183284 99.73% | 25mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-5504 | CH5183284 99.73% | 50mg | $250 | 2021-12-16 | Buy |
| ChemScene | CS-5504 | CH5183284 99.73% | 100mg | $450 | 2021-12-16 | Buy |
| Crysdot | CD31004042 | CH5183284 98+% | 10mg | $216 | 2021-12-16 | Buy |
| Crysdot | CD31004042 | CH5183284 98+% | 25mg | $443 | 2021-12-16 | Buy |
Properties
Boiling point :775.5±55.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥35.6 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :10.51±0.10(Predicted)
CAS DataBase Reference :1265229-25-1
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥35.6 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :10.51±0.10(Predicted)
CAS DataBase Reference :1265229-25-1
Safety Information
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Description
CH5183284 is a potent, selective inhibitor of the kinase activity of fibroblast growth factor receptors (FGFRs) 1, 2, and 3 (IC50s = 9.3, 7.6, and 22 nM, respectively). It less potently inhibits FGFR4 and platelet-derived growth factor receptor β (IC50s = 290 and 560 nM, respectively) and displays IC50 values greater than 1 μM for a diverse panel of tyrosine and serine/threonine kinases. CH5183284 is effective against FGFR2 containing the gatekeeper mutation V564F. Moreover, it inhibits the growth of cancer cells expressing FGFR genetic alterations both in vitro and in xenograft mouse models.Related product price
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