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ChemicalBook >> CAS DataBase List >> Forodesine

Forodesine

Forodesine price.
  • $36 - $660
  • Product name: Forodesine
  • CAS: 209799-67-7
  • MF: C11H14N4O4
  • MW: 266.25
  • EINECS:
  • MDL Number:MFCD09837827
  • Synonyms:4H-Pyrrolo3,2-dpyrimidin-4-one, 7-(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-pyrrolidinyl-1,5-dihydro-;Forodesine;7-[(2S,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-2-pyrrolidinyl]-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one;Fodosine;Immucillin-H;(1S)-1-(9-deazahypoxanthin-9-yl)-1,4-dideoxy-1,4-iMino-D-ribitol, iMMucillin H;FORODESINE FODOSINE;4H-Pyrrolo[3,2-d]pyriMidin-4-one,7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-2-pyrrolidinyl]-3,5-dihydro-
Price9 Properties Safety Information Description
9 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • TRC
Package
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005210
  • Product descriptionFORODESINE 95.00%
  • Packaging5MG
  • Price$660
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number30475
  • Product descriptionForodesine
  • Packaging1mg
  • Price$36
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number30475
  • Product descriptionForodesine
  • Packaging5mg
  • Price$159
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number30475
  • Product descriptionForodesine
  • Packaging10mg
  • Price$194
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number30475
  • Product descriptionForodesine
  • Packaging25mg
  • Price$308
  • Updated2023-06-20
  • Buy
  • ManufacturerChemenu
  • Product numberCM152255
  • Product description7-((2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one 98%
  • Packaging10mg
  • Price$589
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002706
  • Product descriptionFodosine 98+%
  • Packaging5mg
  • Price$347
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002706
  • Product descriptionFodosine 98+%
  • Packaging10mg
  • Price$624
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberF754540
  • Product descriptionFodosine
  • Packaging1mg
  • Price$55
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0005210 FORODESINE 95.00% 5MG $660 2021-12-16 Buy
Cayman Chemical 30475 Forodesine 1mg $36 2023-06-20 Buy
Cayman Chemical 30475 Forodesine 5mg $159 2023-06-20 Buy
Cayman Chemical 30475 Forodesine 10mg $194 2023-06-20 Buy
Cayman Chemical 30475 Forodesine 25mg $308 2023-06-20 Buy
Chemenu CM152255 7-((2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one 98% 10mg $589 2021-12-16 Buy
Crysdot CD31002706 Fodosine 98+% 5mg $347 2021-12-16 Buy
Crysdot CD31002706 Fodosine 98+% 10mg $624 2021-12-16 Buy
TRC F754540 Fodosine 1mg $55 2021-12-16 Buy

Properties

Boiling point :613.5±65.0 °C(Predicted)
Density :2.01
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :PBS (pH 7.2): 5 mg/ml
form :A crystalline solid
pka :13.88±0.70(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Forodesine is a purine nucleoside analog and purine nucleoside phosphorylase (PNP) inhibitor (IC50s = 1.19, 0.48, 1.24, 0.66, and 1.57 nM for human, mouse, rat, monkey, and dog PNP, respectively). It inhibits phytohemagglutinin A-, mixed lymphocyte reaction-, or IL-2-induced proliferation of isolated human peripheral blood lymphocytes (PBLs; IC50s = <0.1-0.38 μM) in the presence, but not absence, of 2’-deoxyguanosine (dGuo). Forodesine inhibits proliferation of CEM-SS T cell acute lymphoblastic leukemia (T-ALL) cells. In vivo, forodesine (10 mg/kg) prolongs survival in the hu-PBL-SCID mouse model of xenogeneic graft versus host disease (GVHD).

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