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ChemicalBook >> CAS DataBase List >> MG-115

MG-115

MG-115 price.
  • $20 - $700
  • Product name: MG-115
  • CAS: 133407-86-0
  • MF: C25H39N3O5
  • MW: 461.59
  • EINECS:
  • MDL Number:MFCD00274411
  • Synonyms:PROTEASOME INHIBITOR MG-115;N-CBZ-LEU-LEU-NORVALINAL;MG-115;Z-LL-NVA-CHO;Z-LEU-LEU-NVA-ALDEHYDE;Z-LEU-LEU-NVA-CHO;Z-LEU-LEU-NVA-H;Z-LEU-LEU-NVA-H (ALDEHYDE)
11 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 2.5mg
  • 5mg
  • 10mg
  • 25mg
  • 100mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CP3-0015-M001
  • Product descriptionZ-Leu-Leu-Nva-CHO[MG-115] ≥95%(HPLC)
  • Packaging1mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2612
  • Product descriptionMG-115
  • Packaging25mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2612
  • Product descriptionMG-115
  • Packaging100mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15413
  • Product description(S)-MG115 ≥95%
  • Packaging1mg
  • Price$51
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15413
  • Product description(S)-MG115 ≥95%
  • Packaging5mg
  • Price$128
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15413
  • Product description(S)-MG115 ≥95%
  • Packaging10mg
  • Price$229
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberC6706
  • Product descriptionZ-Leu-Leu-Norvalinal ≥90% (HPLC), powder
  • Packaging1mg
  • Price$99.3
  • Updated2023-06-20
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberC6706
  • Product descriptionZ-Leu-Leu-Norvalinal ≥90% (HPLC), powder
  • Packaging5mg
  • Price$171.6
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number474780
  • Product descriptionMG-115 Potent reversible proteasome inhibitor (K
  • Packaging5mg
  • Price$259
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberM340978
  • Product descriptionMG-115
  • Packaging2.5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number226813
  • Product descriptionZ-Leu-Leu-Nva-CHO
  • Packaging1mg
  • Price$265
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CP3-0015-M001 Z-Leu-Leu-Nva-CHO[MG-115] ≥95%(HPLC) 1mg $20 2021-12-16 Buy
ApexBio Technology A2612 MG-115 25mg $200 2021-12-16 Buy
ApexBio Technology A2612 MG-115 100mg $700 2021-12-16 Buy
Cayman Chemical 15413 (S)-MG115 ≥95% 1mg $51 2024-03-01 Buy
Cayman Chemical 15413 (S)-MG115 ≥95% 5mg $128 2024-03-01 Buy
Cayman Chemical 15413 (S)-MG115 ≥95% 10mg $229 2024-03-01 Buy
Sigma-Aldrich C6706 Z-Leu-Leu-Norvalinal ≥90% (HPLC), powder 1mg $99.3 2023-06-20 Buy
Sigma-Aldrich C6706 Z-Leu-Leu-Norvalinal ≥90% (HPLC), powder 5mg $171.6 2024-03-01 Buy
Sigma-Aldrich 474780 MG-115 Potent reversible proteasome inhibitor (K 5mg $259 2024-03-01 Buy
TRC M340978 MG-115 2.5mg $90 2021-12-16 Buy
Usbiological 226813 Z-Leu-Leu-Nva-CHO 1mg $265 2021-12-16 Buy

Properties

Boiling point :678.8±55.0 °C(Predicted)
Density :1.082±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble
form :powder
pka :11.14±0.46(Predicted)
color :white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

(S)-MG115 is a potent and reversible proteasome inhibitor, targeting the chymotryptic site on the 20S particle (Ki = 21 nM). It reduces the degradation of ubiquitin-conjugated proteins in extracts. (S)-MG115 also blocks the degradation of long- and short-lived proteins in intact cells as well as the proteolytic generation of diverse proteins, including NF-κB, antigens, and p53. Proteasome inhibitors, including (S)-MG115, can induce a heat shock response and apoptosis, particularly in cancer cells.

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