Tandutinib
|
- $45 - $2500
- Product name: Tandutinib
- CAS: 387867-13-2
- MF: C31H42N6O4
- MW: 562.7
- EINECS:
- MDL Number:MFCD09954147
- Synonyms:Tandutinib;1-Piperazinecarboxamide, 4-(6-methoxy-7-(3-(1-piperidinyl)propoxy)-4-quinazolinyl)-N-(4-(1-methylethoxy)phenyl)-;4-(6-Methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl)piperazine-1-carboxylic acid (4-isopropoxyphenyl)amide;Unii-E1io3icj9a;Tandutinib(CT 53518);Tandutinib (MLN518);CT53518; MLN518;Tandutinib(TINIBS)
31 prices
Selected condition：
Brand
- Adipogen Life Sciences
- ApexBio Technology
- Arctom
- AvaChem
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 2.5mg
- 5mg
- 10mg
- 10mM(in 1mL DMSO)
- 20mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1088-M010
- Product descriptionTandutinib ≥95%
- Packaging10mg
- Price$81
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1526
- Product descriptionTandutinib(MLN518)
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7853
- Product descriptionTandutinib(MLN518)HCl
- Packaging200mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60446
- Product descriptionTandutinib(MLN518)
- Packaging20mg
- Price$98
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2203
- Product descriptionTandutinib
- Packaging25mg
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2203
- Product descriptionTandutinib
- Packaging100mg
- Price$269
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2203
- Product descriptionTandutinib
- Packaging1g
- Price$890
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFT28001
- Product descriptionTandutinib
- Packaging10mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFT28001
- Product descriptionTandutinib
- Packaging50mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number12098
- Product descriptionTandutinib ≥95%
- Packaging25mg
- Price$56
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number12098
- Product descriptionTandutinib ≥95%
- Packaging50mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number12098
- Product descriptionTandutinib ≥95%
- Packaging100mg
- Price$140
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number12098
- Product descriptionTandutinib ≥95%
- Packaging250mg
- Price$311
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0128
- Product descriptionTandutinib 99.48%
- Packaging50mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0128
- Product descriptionTandutinib 99.48%
- Packaging100mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0128
- Product descriptionTandutinib 99.48%
- Packaging200mg
- Price$168
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1088-M010 | Tandutinib ≥95% | 10mg | $81 | 2021-12-16 | Buy |
| ApexBio Technology | B1526 | Tandutinib(MLN518) | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B7853 | Tandutinib(MLN518)HCl | 200mg | $140 | 2021-12-16 | Buy |
| Arctom | CFN60446 | Tandutinib(MLN518) | 20mg | $98 | 2021-12-16 | Buy |
| AvaChem | 2203 | Tandutinib | 25mg | $129 | 2021-12-16 | Buy |
| AvaChem | 2203 | Tandutinib | 100mg | $269 | 2021-12-16 | Buy |
| AvaChem | 2203 | Tandutinib | 1g | $890 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FT28001 | Tandutinib | 10mg | $45 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FT28001 | Tandutinib | 50mg | $158 | 2021-12-16 | Buy |
| Cayman Chemical | 12098 | Tandutinib ≥95% | 25mg | $56 | 2024-03-01 | Buy |
| Cayman Chemical | 12098 | Tandutinib ≥95% | 50mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 12098 | Tandutinib ≥95% | 100mg | $140 | 2024-03-01 | Buy |
| Cayman Chemical | 12098 | Tandutinib ≥95% | 250mg | $311 | 2024-03-01 | Buy |
| ChemScene | CS-0128 | Tandutinib 99.48% | 50mg | $60 | 2021-12-16 | Buy |
| ChemScene | CS-0128 | Tandutinib 99.48% | 100mg | $96 | 2021-12-16 | Buy |
| ChemScene | CS-0128 | Tandutinib 99.48% | 200mg | $168 | 2021-12-16 | Buy |
Properties
Melting point :177-178°C
Boiling point :769.5±60.0 °C(Predicted)
Density :1.213±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :13.39±0.70(Predicted)
form :Solid
color :White to Off-White
CAS DataBase Reference :387867-13-2(CAS DataBase Reference)
Boiling point :769.5±60.0 °C(Predicted)
Density :1.213±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :13.39±0.70(Predicted)
form :Solid
color :White to Off-White
CAS DataBase Reference :387867-13-2(CAS DataBase Reference)
Safety Information
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Description
Tandutinib is a potent antagonist of platelet-derived growth factor receptor β (PDGFRβ), FLT3, and c-Kit (IC50 = 200, 220, and 170 nM, respectively). It less potently inhibits macrophage colony-stimulating factor 1 receptor (IC50 = 3.4 μM) and does not significantly inhibit other tyrosine or serine/threonine kinases. Tandutinib blocks the growth of cells expressing an internal tandem duplication within the juxtamembrane domain of the FLT3 receptor, found in some acute myelogenous leukemia cells. It also impairs the growth of colon cancer cells through its actions on the c-Kit receptor. Tandutinib reverses multidrug resistance in vitro by impairing the efflux activity of the multidrug resistance protein 7.Related product price
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