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ChemicalBook >> CAS DataBase List >> Tegaserod maleate

Tegaserod maleate

Tegaserod maleate price.
  • $6 - $1890
  • Product name: Tegaserod maleate
  • CAS: 189188-57-6
  • MF: C20H27N5O5
  • MW: 417.46
  • EINECS:630-469-2
  • MDL Number:MFCD04116201
  • Synonyms:SDZ-HTF-919;TEGASEROD MALEATE;ZELMAC;2-[(5-METHOXY-1H-INDOL-3-YL)METHYLENE]-N-PENTYLHYDRAZINECARBOXIMIDAMIDE, MALEATE;2-[(5-methoxy-1h-indole-3-yl)methylene]-n-pentylcarbazimidamide hydrogen maleate;TegaserodMalate;TegastrodMaleate;SDZ-HTF-919, Zelmac, 2-[(5-Methoxy-1H-indol-3-yl)methylene]-N-pentylhydrazinecarboximidamide, Maleate
32 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 0.1g
  • 100mg
  • 10
  • 250mg
  • 50
  • 1g
  • 5g
  • ManufacturerAHH
  • Product numberAPI-1749
  • Product descriptionTegaserodmaleate 98%
  • Packaging0.1g
  • Price$730
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH172
  • Product descriptionTegaserodmaleate
  • Packaging50mg
  • Price$295
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA670060
  • Product descriptionTegaserodmaleate 98+%
  • Packaging10mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA670060
  • Product descriptionTegaserodmaleate 98+%
  • Packaging100mg
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA670060
  • Product descriptionTegaserodmaleate 98+%
  • Packaging250mg
  • Price$33
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA670060
  • Product descriptionTegaserodmaleate 98+%
  • Packaging1g
  • Price$83
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7690
  • Product descriptionTegaserodmaleate
  • Packaging10mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7690
  • Product descriptionTegaserodmaleate
  • Packaging50mg
  • Price$457
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2786
  • Product descriptionTegaserod Maleate
  • Packaging5mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2786
  • Product descriptionTegaserod Maleate
  • Packaging10mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2786
  • Product descriptionTegaserod Maleate
  • Packaging25mg
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2786
  • Product descriptionTegaserod Maleate
  • Packaging100mg
  • Price$249
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2786
  • Product descriptionTegaserod Maleate
  • Packaging250mg
  • Price$349
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2786
  • Product descriptionTegaserod Maleate
  • Packaging1g
  • Price$649
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2786
  • Product descriptionTegaserod Maleate
  • Packaging5g
  • Price$1890
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT28020
  • Product descriptionTegaserod maleate
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1749 Tegaserodmaleate 98% 0.1g $730 2021-12-16 Buy
AK Scientific H172 Tegaserodmaleate 50mg $295 2021-12-16 Buy
Ambeed A670060 Tegaserodmaleate 98+% 10mg $6 2021-12-16 Buy
Ambeed A670060 Tegaserodmaleate 98+% 100mg $16 2021-12-16 Buy
Ambeed A670060 Tegaserodmaleate 98+% 250mg $33 2021-12-16 Buy
Ambeed A670060 Tegaserodmaleate 98+% 1g $83 2021-12-16 Buy
ApexBio Technology B7690 Tegaserodmaleate 10mg $145 2021-12-16 Buy
ApexBio Technology B7690 Tegaserodmaleate 50mg $457 2021-12-16 Buy
AvaChem 2786 Tegaserod Maleate 5mg $39 2021-12-16 Buy
AvaChem 2786 Tegaserod Maleate 10mg $59 2021-12-16 Buy
AvaChem 2786 Tegaserod Maleate 25mg $109 2021-12-16 Buy
AvaChem 2786 Tegaserod Maleate 100mg $249 2021-12-16 Buy
AvaChem 2786 Tegaserod Maleate 250mg $349 2021-12-16 Buy
AvaChem 2786 Tegaserod Maleate 1g $649 2021-12-16 Buy
AvaChem 2786 Tegaserod Maleate 5g $1890 2021-12-16 Buy
Biosynth Carbosynth FT28020 Tegaserod maleate 10mg $80 2021-12-16 Buy

Properties

Melting point :180-183°C
storage temp. :2-8°C
solubility :Acetonitrile (Slightly, Heated), DMSO (Slightly), Methanol (Sparingly)
form :powder
color :white to beige
CAS DataBase Reference :189188-57-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P321 Specific treatment (see … on this label).
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P363 Wash contaminated clothing before reuse.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

Tegaserod (maleate) is a potent agonist of the serotonin 4 receptor (5-HT4, Ki = 3.9-31 nM). As 5-HT4 receptors are associated with cholinergic nerves lining the colon, tegaserod (maleate) stimulates colonic motility and transit in vivo, in both healthy and diseased gastrointestinal tracts. However, it lacks selectivity, since it also acts as an antagonist for the 5-HT2A, 5-HT2B, and 5-HT2C receptors (Ki = 32, 3.9, and 100 nM, respectively). It is a weak agonist of 5-HT3 (Ki ≤ 10 μM).

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