| | 1257044-40-8 Basic information More.. |
| Product Name: | ABT-199 | | Synonyms: | ABT-199;ABT-199 (GDC-0199);GDC-0199;ABT-199 100MG;2-(1H-Pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)met;ABT-199, Venetoclax;GDC 0199;GDC0199;Benzamide, 4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)- | | CAS: | 1257044-40-8 | | MF: | C45H50ClN7O7S | | MW: | 868.44 | | EINECS: | 820-130-9 | | Mol File: | 1257044-40-8.mol |  |
Use
ABT-199, also known as venetoclax, is a small, oral chemical molecule used for the treatment of chronic lymphocytic leukemia (CLL) associated with a specific chromosomal abnormality. As a second line treatment drug of CLL, ABT-199 take effects through acting as a BH3-mimetic and inhibitor of Bcl-2 (the anti-apoptotic B-cell lymphoma-2protein), further inducing apoptosis of CLL cells but not platelets. It also has the potential for the treatment of ER-positive breast cancer.
- ABT-199
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- US $10.00 / ASSAYS
- 2024-05-08
- CAS:1257044-40-8
- Min. Order: 1ASSAYS
- Purity: 99%
- Supply Ability: 10 ton
- Venetoclax
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- US $0.00-0.00 / mg
- 2024-04-28
- CAS:1257044-40-8
- Min. Order: 10mg
- Purity: 0.98
- Supply Ability: 10g
- ABT-199
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- US $0.00 / kg
- 2024-04-12
- CAS:1257044-40-8
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 10T
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1257044-40-8
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