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| | 2-Hydroxy-2-methylpropiophenone Basic information | | Uses |
| | 2-Hydroxy-2-methylpropiophenone Chemical Properties |
| Melting point | 4°C | | Boiling point | 102-103 °C4 mm Hg(lit.) | | density | 1.077 g/mL at 25 °C(lit.) | | vapor pressure | 0.57Pa at 20℃ | | refractive index | n20/D 1.533(lit.) | | Fp | >230 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Practically insoluble in water | | form | clear liquid | | pka | 13.23±0.29(Predicted) | | Specific Gravity | 1.077 | | color | Colorless to Light orange to Yellow | | Water Solubility | 13.3g/L at 20℃ | | InChIKey | XMLYCEVDHLAQEL-UHFFFAOYSA-N | | LogP | 1.62 at 25℃ | | CAS DataBase Reference | 7473-98-5(CAS DataBase Reference) | | EPA Substance Registry System | 1-Propanone, 2-hydroxy-2-methyl-1-phenyl- (7473-98-5) |
| Hazard Codes | Xn | | Risk Statements | 22 | | Safety Statements | 23-36/37/39 | | RIDADR | 3082 | | WGK Germany | 3 | | RTECS | UC2977245 | | HazardClass | 9 | | PackingGroup | III | | HS Code | 29144000 |
| | 2-Hydroxy-2-methylpropiophenone Usage And Synthesis |
| Uses | 2-Hydroxy-2-methylpropiophenone is a photoinitiator.In addition, 2-hydroxy-2-methylpropiophenone is an important organic intermediate (building block) to synthetize substituted propiophenone products.
| | Chemical Properties | Yellowish clear liquid | | Uses | 2-Hydroxy-2-benzoylpropane was used as a catalyst in real-time kinetic study of laser-induced polymerization. It is also a photoinitiator. | | Synthesis Reference(s) | Tetrahedron Letters, 29, p. 4365, 1988 DOI: 10.1016/S0040-4039(00)80496-7 | | General Description | 2-Hydroxy-2-methylpropiophenone is a radical photoinitiator (PI) molecule that can be used in the crosslinking of polymers by the exposure of UV radiation. It can be used in the development of UV curable resins for exterior coating applications. | | Hazard | Moderately toxic by ingestion. | | Flammability and Explosibility | Not classified | | Synthesis | KBr in water is added to a solution of 2-methyl-1-phenylpropane-1,2-diol in toluene. Then, TEMPO is added. The reddish suspension is cooled to 0°C. A 12 % sodium hypochlorite solution is added while maintaining the internal temperature at 5°C or lower. The mixture is stirred for 1 h at 0-5°C and then separated for 10 min. Sodium dithionite solution (obtained from 30 g sodium dithionite (85%) and 400 ml of water)is added to the organic phase and stirred at 85°C for 1-2 h. The organic phase is again separated and concentrated (rotavap). The crude product is then subjected to fractional distillation, yielding 2-Hydroxy-2-methylpropiophenone as a colorless oil.
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| | 2-Hydroxy-2-methylpropiophenone Preparation Products And Raw materials |
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