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| | [2-(aminomethyl)phenyl]methanol Basic information |
| | [2-(aminomethyl)phenyl]methanol Chemical Properties |
| Boiling point | 271℃ | | density | 1.113 | | Fp | 118℃ | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 14.28±0.10(Predicted) |
| | [2-(aminomethyl)phenyl]methanol Usage And Synthesis |
| Uses | [2-(aminomethyl)phenyl]methanol can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | | Uses | (2-(Aminomethyl)phenyl)methanol is a useful research intermediate for the total synthesis of Adalinine. | | Synthesis | (4-Aminomethyl-phenyl)-methanol hydrochloride salt 4-Hydroxymethyl-benzonitrile (2.0 g, 15 mol) was reduced using Raney nickel (0. 5g) and hydrogen (50 psi) in MeOH: NH3 (100ml) for 20 hours. The reaction mixture was filtered through a pad of celite. The filtrate was concentrated under reduced pressure to afford (4-aminomethyl-phenyl)-methanol hydrochloride salt (2.01 g, 98percent) as a white solid of sufficient purity for use without further purification: MS (APCI+) : m/z 138.3 (M+H). |
| | [2-(aminomethyl)phenyl]methanol Preparation Products And Raw materials |
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