(5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER manufacturers
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| | (5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER Basic information |
| Product Name: | (5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER | | Synonyms: | (5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER;(5-BROMOPYRAZINYL)CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER;tert-Butyl (5-bromopyrazin-2-yl);N-Boc-2-Amino-5-bromopyrazine;2-Amino-5-bromopyrazine, 2-BOC;CarbaMicacid,(5-broMopyrazinyl)-,1,1-diMethylethylester;2-Amino-5-bromopyrazine, 2-BOC protected;tert-Butyl (5-bromopyrazin-2-yl)carbamate, 2-Bromo-5-[(tert-butoxycarbonyl)amino]-1,4-diazine | | CAS: | 914349-79-4 | | MF: | C9H12BrN3O2 | | MW: | 274.11 | | EINECS: | | | Product Categories: | | | Mol File: | 914349-79-4.mol |  |
| | (5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER Chemical Properties |
| Boiling point | 295.2±40.0 °C(Predicted) | | density | 1.513±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | 10.75±0.70(Predicted) |
| Hazard Codes | Xn | | Risk Statements | 22 | | HS Code | 2933998090 |
| | (5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER Usage And Synthesis |
| Uses | (5-BROMOPYRAZIN-2-YL) CARBAMIC ACID TERT-BUTYL ESTER can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | | Synthesis | 
At 0 ??, to 5-bromopyrazine-2-amine (5736.8mg, 32.97mmol) in CH2Cl2 (80mL) solution was added 4-DMAP (403.2mg, 3.30mmol); then at 0 ?? drop two A solution of di-tert-butyl carbonate (11.4ml, 3.30mmol) in CH2Cl2; the mixture was stirred at room temperature; after the completion of the reaction was monitored by TLC, the solution was washed with brine, dried over Na2SO4, filtered, and concentrated in vacuo; the crude product was chromatographed on a silica gel column Method, purified with ethyl acetate/petroleum ether (1/2) to obtain a white solid product (7250.4 mg, yield 80.2%). |
| | (5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER Preparation Products And Raw materials |
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