| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
| Products Intro: |
Product Name:Cyclic adenosine diphosphate-ribose
CAS:119340-53-3
Purity:>=90% (HPLC) Package:250μg, 0.5mg Remarks:C7344
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| | CADP-RIBOSE Basic information |
| Product Name: | CADP-RIBOSE | | Synonyms: | CADPR;CADP-RIBOSE;ADP-CYCLO-[N1:1'']-RIBOSE;CADPR SODIUM SALT;cyclicadenosinediphosphateribose(cadpr),sodiumsalt;CYCLIC ADP RIBOSE POTENT INTRACELLULAR;ADP-cyclo[N1:1μμ]-ribose, cADP-ribose, cADPR, Cyclic ADPR;C13050 | | CAS: | 119340-53-3 | | MF: | C15H21N5O13P2 | | MW: | 541.3 | | EINECS: | | | Product Categories: | | | Mol File: | 119340-53-3.mol |  |
| | CADP-RIBOSE Chemical Properties |
| Boiling point | 934.8±75.0 °C(Predicted) | | density | 2.57±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMSO (Slightly), Methanol (Very Slightly), Water (Slightly) | | pka | 0.97±0.70(Predicted) | | form | lyophilized powder | | Stability: | Hygroscopic |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 |
| | CADP-RIBOSE Usage And Synthesis |
| Uses | Cyclic adenosine diphosphate-ribose (cADPR) is an intracellular second messenger that mobilizes intracellular Ca2+ release from the sarcoplasmic reticulum through ryanodine receptors. CADPR is also a second messenger for glucose-induced insulin release from endocrine pancreas and for abscisic acid-induced calcium release in plants. | | Definition | ChEBI: A cyclic purine nucleotide that is synthesised from NAD+ by ADP-ribosyl cyclase; acts as an agonist at ryanodine receptors. | | Biochem/physiol Actions | Mobilizes intracellular Ca2+; regulates Ca2+-induced Ca2+?release specifically blocked by ryanodine; second messenger for glucose-induced insulin release from the endocrine pancreas and for abscisic acid-induced calcium release in plants. |
| | CADP-RIBOSE Preparation Products And Raw materials |
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