Company Name: |
Lynnchem
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Tel: |
86-(0)29-85992781 17792393971 |
Email: |
info@lynnchem.com |
Products Intro: |
Product Name:BROMAMPHENICOL CAS:16803-75-1 Purity:>99% by HPLC Package:5mg;25mg
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Company Name: |
Novachemistry
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Tel: |
44-20819178-90 02081917890 |
Email: |
info@novachemistry.com |
Products Intro: |
Product Name:Bromamphenicol CAS:16803-75-1 Purity:>99% by HPLC Package:5mg;25mg
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| BROMAMPHENICOL Basic information |
Product Name: | BROMAMPHENICOL | Synonyms: | Acetamide, 2,2-dibromo-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]- | CAS: | 16803-75-1 | MF: | C11H12Br2N2O5 | MW: | 412.03 | EINECS: | | Product Categories: | | Mol File: | 16803-75-1.mol | |
| BROMAMPHENICOL Chemical Properties |
Melting point | 155-156 °C | Boiling point | 664.4±55.0 °C(Predicted) | density | 1.939±0.06 g/cm3(Predicted) | pka | 11.14±0.46(Predicted) |
| BROMAMPHENICOL Usage And Synthesis |
Uses | Bromamphenicol is a semi-synthetic chloramphenicol analogue first reported in 1950, in which the dichloroacetamide is replaced with dibromoacetamide. Bromamphenicol possesses weak antibiotic activity. Comparative crystallography with chloramphenicol helped defined the SARs of the acetamide binding region on the ribosome. More recently, this relationship was used to demonstrate that chloramphenicol binding to DraE virulence factors in Gram negative bacteria was independent of chloramphenicol binding site on the ribosome. | Uses | Bromamphenicol is a semi-synthetic chloramphenicol analogue in which the dichloroacetamide is replaced with dibromoacetamide, first reported in 1950. Bromamphenicol possesses weak antibiotic activity. Comparative crystallography with chloramphenicol helped defined the SARs of the acetamide binding region on the ribosome. More recently, this relationship was used to demonstrate that chloramphenicol binding to DraE virulence factors in Gram negative bacteria was independent of chloramphenicol binding site on the ribosome. |
| BROMAMPHENICOL Preparation Products And Raw materials |
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