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| | N-Desethyl Vardenafil Basic information |
| Product Name: | N-Desethyl Vardenafil | | Synonyms: | 1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-piperazine;Vardenafil Impurity 4(Vardenafil N-Desethyl Impurity);2-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one;Vardenafil N-Desethyl Impurity;Vardenafil N-Desethyl Imp;N-Desethyl Vardenafil Impurity;2-(2-ethoxy-5-piperazin-1-ylsulfonylphenyl)-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one;2-(2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one | | CAS: | 448184-46-1 | | MF: | C21H28N6O4S | | MW: | 460.55 | | EINECS: | | | Product Categories: | Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals | | Mol File: | 448184-46-1.mol |  |
| | N-Desethyl Vardenafil Chemical Properties |
| Boiling point | 699.8±65.0 °C(Predicted) | | density | 1.44±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer, Under Inert Atmosphere | | solubility | DMF: 30mg/mL; DMSO: 30 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/mL | | form | A crystalline solid | | pka | 7.73±0.10(Predicted) |
| | N-Desethyl Vardenafil Usage And Synthesis |
| Description | N-Desethyl vardenafil is a metabolite of vardenafil , a phosphodiesterase 5 inhibitor, that is formed by the action of cytochrome P450 (CYP)3A4 and CYP3A5. | | Chemical Properties | White to Off-White Solid | | Uses | N-Desethyl Vardenafil is a metabolite of Vardenafil, a phosphodiesterase 5 inhibitor. |
| | N-Desethyl Vardenafil Preparation Products And Raw materials |
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