Bentazepam manufacturers
- Bentazepam
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- $1.00 / 1g
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2024-05-15
- CAS:29462-18-8
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 100kg
- Bentazepam
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- $0.00 / 1kg
-
2024-04-12
- CAS:29462-18-8
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 10T
- Bentazepam
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- $150.00 / 1kg
-
2023-06-13
- CAS:29462-18-8
- Min. Order: 1kg
- Purity: 99.9%
- Supply Ability: 10000MT
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| | Bentazepam Basic information |
| Product Name: | Bentazepam | | Synonyms: | Bentazepam;1,3,6,7,8,9-Hexahydro-5-phenyl-2H-[1]benzothieno[2,3-e]-1,4-diazepin-2-one;CI-718;QM-6008;Thiadipon;Thiadipone;5-Phenyl-6,7,8,9-tetrahydro-1H-benzo[4,5]thieno[2,3-e][1,4]diazepin-2(3H)-one;2H-[1]Benzothieno[2,3-e]-1,4-diazepin-2-one, 1,3,6,7,8,9-hexahydro-5-phenyl- | | CAS: | 29462-18-8 | | MF: | C17H16N2OS | | MW: | 296.39 | | EINECS: | | | Product Categories: | | | Mol File: | 29462-18-8.mol |  |
| | Bentazepam Chemical Properties |
| Melting point | 249.5°C | | Boiling point | 197.5°C (rough estimate) | | density | 1.1654 (rough estimate) | | refractive index | 1.7400 (estimate) | | solubility | DMF:15.0(Max Conc. mg/mL);50.61(Max Conc. mM)
DMSO:15.0(Max Conc. mg/mL);50.61(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.84(Max Conc. mM) | | form | A crystalline solid | | pka | 13.24±0.40(Predicted) | | Stability: | Hygroscopic |
| Toxicity | LD50 oral in rat: 2gm/kg |
| | Bentazepam Usage And Synthesis |
| Originator | Bentazepam,Laboratorios Made S. A. | | Uses | Sedative-hypnotic. | | Definition | ChEBI: Bentazepam is an organosulfur heterocyclic compound and an organonitrogen heterocyclic compound. | | Manufacturing Process | To a solution of 3.4 kg N-phthalimidoacetic acid in 20 L of methylene chloride
was added a solution of 2.8 kg of 1,1-carbonyl diimidazol in 20 L of methylene
chloride. The mixture was refluxed for 1 hour. After cooling to the obtained
solution was added a solution of 4.3 kg of 2-amino-3-benzoyl-4,5-
tetramethylene thiophene in 30 L of methylene chloride and the reaction
mixture was refluxed for 16 hours. After cooling the mixture was washed with
30 L of water, dried with sodium sulfate and filtered. After removing the
solvent was obtained the 2-(N-phthalimidoacetylamino)-3-benzoyl-4,5-
tetramethylene thiophene, yield 70%, melting point 230°C. | | Therapeutic Function | Anticonvulsant, Tranquilizer | | Safety Profile | Moderately toxic by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic fumes of SOx and NOx. |
| | Bentazepam Preparation Products And Raw materials |
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