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| | 5-Methyltryptamine hydrochloride Basic information |
| Product Name: | 5-Methyltryptamine hydrochloride | | Synonyms: | 5-METHYLTRYPTAMNE HCL 98.0%MIN;2-(5-METHYL-1H-INDOL-3-YL)ETHYLAMINE HYDROCHLORIDE;2-(5-METHYL-1H-INDOL-3-YL)ETHANAMINE HYDROCHLORIDE;2-[5-METHYLINDOL-3-YL]ETHYLAMINE HYDROCHLORIDE;3-(2-AMINOETHYL)-5-METHYLINDOLE HYDROCHLORIDE;3-(2-AMINOETHYL)-5-METHYLINDOLE HCL;5-METHYLTRYPTAMINE HCL;5-METHYLTRYPTAMINE HYDROCHLORIDE | | CAS: | 1010-95-3 | | MF: | C11H15ClN2 | | MW: | 210.7 | | EINECS: | 213-777-8 | | Product Categories: | | | Mol File: | 1010-95-3.mol |  |
| | 5-Methyltryptamine hydrochloride Chemical Properties |
| Melting point | 290-292 °C | | solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) | | form | Solid | | color | Pale Beige to Light Tan | | Sensitive | Hygroscopic | | CAS DataBase Reference | 1010-95-3 |
| Hazard Codes | T+ | | Risk Statements | 26/27/28 | | Safety Statements | 22-24/25 | | RIDADR | 2811 | | WGK Germany | 3 | | F | 10 | | HazardClass | 6.1 | | PackingGroup | Ⅲ |
| | 5-Methyltryptamine hydrochloride Usage And Synthesis |
| Chemical Properties | Light Tan Solid | | Uses | - reactant in synthesis of kinesin spindle protein (KSP) inhibitors
- reactant in intramolecular furan Diels-Alder reactions
- reactant in Pictet-Spengler-like reactions
| | Uses | 5-Methyltryptamine hydrochloride is a methylated derivative of tryptamine, it is a weak antagonist of 5-Hydroxytryptamine (H974990) with weak potency as stimulants of the cardiac sympathetic nerves. 5-Methyltryptamine hydrochloride is also used in the preparation of inhibitors of kinesin spindle protein (KSP), a promising class of anticancer agents. | | Purification Methods | Recrystallise the hydrochloride from H2O. The free base has m 96-98o (from *C6H6/cyclohexane) or m 99-100o (from pet ether), and the picrate has m 243o(dec) (from EtOH). [Young J Chem Soc 3493 1958, Gaddum et al. Quart J Exp Physiol 40 49 1955, R.hm Hoppe Seyler's Z Physiol Chem 297 229 1954, Beilstein 22 III/IV 4364, 22/10 V 167.] |
| | 5-Methyltryptamine hydrochloride Preparation Products And Raw materials |
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