| Company Name: |
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788 |
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jkinfo@jkchemical.com |
| Products Intro: |
Product Name:MNI-caged-L-glutaMate
CAS:295325-62-1
Package:100Mg,10Mg,50Mg
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| | (S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID Basic information |
| Product Name: | (S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID | | Synonyms: | MNI-CAGED-L-GLUTAMATE;(S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID;(S)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-1H-indole-1-pentanoicacid;GXIDBZKXGUNITQ-VIFPVBQESA-N;(S)-2-Amino-5-(4-methoxy-7-nitro-1-indolinyl)-5-oxopentanoic Acid;(2S)-2-amino-5-(4-methoxy-7-nitro-2,3-dihydroindol-1-yl)-5-oxopentanoic acid;1H-Indole-1-pentanoic acid, α-amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-, (αS)-;MNI-caged-L-glutamat | | CAS: | 295325-62-1 | | MF: | C14H17N3O6 | | MW: | 323.3 | | EINECS: | | | Product Categories: | | | Mol File: | 295325-62-1.mol |  |
| | (S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID Chemical Properties |
| Melting point | >160°C (dec.) | | Boiling point | 675.1±55.0 °C(Predicted) | | density | 1.437±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Methanol (Slightly), Water (Slightly) | | form | Solid | | pka | 2.20±0.10(Predicted) | | color | Light Yellow | | Water Solubility | Soluble to 50 mM in water with gentle warming |
| | (S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID Usage And Synthesis |
| Uses | MNI-caged-L-glutamate, is a new caged neuroactive amino acid, that use 4-methoxy-7-nitroindolinyl- (MNI) group to make caged ligands specific for glutamate receptor sub-types. MNI-caged-L-glutamate, rapidly release glutamate when photolysed. | | Biological Activity | Caged glutamate that rapidly and efficiently releases glutamate when photolysed (300-380 nm excitation). Water-soluble, highly resistant to hydrolysis, stable at neutral pH, and pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations). 2.5-fold more efficient at releasing L-glutamate than NI-caged L-glutamate. | | storage | -20°C (protect from light) |
| | (S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID Preparation Products And Raw materials |
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