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AC-ARG-TYR-TYR-ARG-ILE-LYS-NH2

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Company Name: Shenzhen Nexconn Pharmatechs Ltd
Tel: +86-755-89396905 +86-15013857715
Email: admin@nexconn.com
Products Intro: Product Name:Ac-RYYRIK-NH2
CAS:200959-48-4
Purity:98% Package:1KG;10KG;50KG
Company Name: Career Henan Chemica Co
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Products Intro: Product Name:AC-ARG-TYR-TYR-ARG-ILE-LYS-NH2
CAS:200959-48-4
Purity:99% Package:1KG;7USD
Company Name: BOC Sciences
Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:Ac-RYYRIK-NH
CAS:200959-48-4
Remarks:BOC Sciences also provides custom synthesis services for Ac-RYYRIK-NH.
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471
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Products Intro: CAS:200959-48-4
Purity:99% Package:5KG;1KG
Company Name: Hangzhou Go Top Peptide Biotech
Tel: 0571-88211921
Email: sales1@gotopbio.com
Products Intro: Product Name:Ac-RYYRIK-NH2
CAS:200959-48-4
Purity:99% HPLC、MS Package:1mg/ plastic bottle ,customer's requirement packaging also welcome
AC-ARG-TYR-TYR-ARG-ILE-LYS-NH2 Basic information
Product Name:AC-ARG-TYR-TYR-ARG-ILE-LYS-NH2
Synonyms:AC-ARG-TYR-TYR-ARG-ILE-LYS-NH2;ACETYL-RYYRIK, AMIDE;AC-RYYRIK-NH2;Ac-RYYRIK amide;Ac-RYYRIK-NH;L-Lysinamide, N2-acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-isoleucyl-;N2-Acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-isoleucyl-L-lysinamide
CAS:200959-48-4
MF:C44H70N14O9
MW:939.11
EINECS:
Product Categories:Opioid receptor and opioid-like receptor
Mol File:200959-48-4.mol
AC-ARG-TYR-TYR-ARG-ILE-LYS-NH2 Structure
AC-ARG-TYR-TYR-ARG-ILE-LYS-NH2 Chemical Properties
density 1.39±0.1 g/cm3(Predicted)
storage temp. -15°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka9.82±0.15(Predicted)
Safety Information
Safety Statements 22-24/25
MSDS Information
AC-ARG-TYR-TYR-ARG-ILE-LYS-NH2 Usage And Synthesis
Biological ActivityAc-RYYRIK-NH2 is a potent ORL1 partial agonist as an endogenous ligand of ORL1 in CHO cells (Kd=1.5 nM). Ac-RYYRIK-NH2 is a specific antagonist of G protein activation and competitively antagonizes noc/OFQ-stimulated [35S]-GTPgS-binding G protein in rat meninges and brain sections.
in vivo

Ac-RYYRIK-NH2 (intracerebroventricularly (icv) inhibits spontaneous locomotor activity in mice with an ID 50 of 0.07 nmol. Co-administration of noc/OFQ and Ac-RYYRIK-NH2

target

Kd: 1.5 nM (ORL1 transfected in CHO cells)

AC-ARG-TYR-TYR-ARG-ILE-LYS-NH2 Preparation Products And Raw materials
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AC-ARG-TYR-TYR-ARG-ILE-LYS-NH2