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treosulfan

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treosulfan Suppliers list
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:Treosulfan
CAS:299-75-2
Package:25mg Remarks:BOC Sciences also provides custom synthesis services for Treosulfan.
Company Name: career henan chemical co
Tel: +86-0371-86658258 15093356674;
Email: factory@coreychem.com
Products Intro: Product Name:treosulfan
CAS:299-75-2
Purity:98% Package:1KG;1USD
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Treosulfan；NSC 39069;Treosulphan
CAS:299-75-2
Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:Treosulfan (NSC-39069; Treosulphan)
CAS:299-75-2
Purity:98% Package:5mg Remarks:V5077
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
Tel: +undefined18051384581
Email: sales@chemhifuture.com
Products Intro: Product Name:Treosulfan
CAS:299-75-2
Purity:98% HPLC Package:mg，g

treosulfan manufacturers

  • Treosulfan
  • Treosulfan pictures
  • $46.00 / 1kg
  • 2024-01-08
  • CAS:299-75-2
  • Min. Order: 1kg
  • Purity: 99.50%
  • Supply Ability: 20tons
  • treosulfan
  • treosulfan pictures
  • $1.00 / 1KG
  • 2020-01-15
  • CAS:299-75-2
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 1kg ,5kg, 50kg
treosulfan Basic information
Product Name:treosulfan
Synonyms:TREOSULPHAN;1,2,3,4-butanetetrol 1,4-dimethanesulfonate;(2S,3S)-1-O,4-O-Di(methylsulfonyl)-L-threitol;CB-2562;L-Dihydroxy-Busulfan;Leo 40067;NSC 39069;THREOSULFAN
CAS:299-75-2
MF:C6H14O8S2
MW:278.3
EINECS:206-081-0
Product Categories:API
Mol File:299-75-2.mol
treosulfan Structure
treosulfan Chemical Properties
Melting point 76-78 °C
Boiling point 359.3°C (rough estimate)
density 1.305 (estimate)
refractive index 1.5630 (estimate)
storage temp. Store at -20°C
solubility Acetone (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
pka12.36±0.20(Predicted)
color Off-White to Pale Beige
CAS DataBase Reference299-75-2
IARC1 (Vol. 26, Sup 7, 100A) 2012
EPA Substance Registry SystemTreosulfan (299-75-2)
Safety Information
RIDADR 2811
HazardClass 6.1(b)
PackingGroup III
Hazardous Substances Data299-75-2(Hazardous Substances Data)
ToxicityLDLo intravenous in dog: 222mg/kg
MSDS Information
treosulfan Usage And Synthesis
UsesTreosulfan is used as myeloablative agent in conditioning regimen prior to allogeneic hematopoietic stem cell transplantation (HSCT)??. It can also be an effective agent for conditioning children with inborn errors of immunity (IEI).
DefinitionChEBI: Treosulfan is a methanesulfonate ester.
General DescriptionOdorless white crystalline powder.
Air & Water ReactionsWater soluble. Slowly hydrolyzes: decomposes within 3 hours at pH 7.5 and 77°F. .
Fire HazardFlash point data for treosulfan are not available; however, treosulfan is probably combustible.
Clinical UseAlkylating agent for ovarian cancer
Safety ProfileConfirmed carcinogen. Poison by intravenous route. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx.
MetabolismTreosulfan is a prodrug of a bifunctional alkylating agent, converted in vivo to epoxide compounds. Approximately 30
% of the substance is excreted unchanged in the urine within 24 hours, nearly 90
% of which is within the first 6 hours after administration.
treosulfan Preparation Products And Raw materials
Tag:treosulfan(299-75-2) Related Product Information
Cyclophosphamide monohydrate (+)-1 4-DI-O-TOSYL-D-THREITOL (+)-1,4-DI-O-TOSYL-2,3-O-ISOPROPYLIDENE-D-THREITOL Busulfan (+)-2,3-O-ISOPROPYLIDENE-D-THREITOL 1,4-DIMETHANE SULFONATE treosulfan