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Fencamfamin

Fencamfamin Basic information
Product Name:Fencamfamin
Synonyms:Fencamfamin;fencamfamine;Euvitol;Glucoenergan;N-Ethyl-3-phenylbicyclo[2.2.1]heptan-2-amine;Fencamfamin HCl;(1R,4S)-N-ethyl-2-phenylbicyclo[2.2.1]heptan-3-amine;N-ethyl-2-phenylbicyclo[2.2.1]heptan-3-amine
CAS:1209-98-9
MF:C15H21N
MW:0
EINECS:
Product Categories:
Mol File:1209-98-9.mol
Fencamfamin Structure
Fencamfamin Chemical Properties
Boiling point bp0.1 128-131°
pkapKa 8.70 (Uncertain)
Safety Information
DEA Controlled SubstancesCSCN: 1760
CAS SCH: IV
NARC: N
MSDS Information
Fencamfamin Usage And Synthesis
OriginatorFencamfamin,Shanghai Lansheng
DefinitionChEBI: Fencamfamin is a monoterpenoid.
Manufacturing Process1) 28.05 g of 2-phenyl-3-aminobicyclo[2.2.1]heptane are mixed with 6.9 g acetaldehyde keeping the mixture cool. The mixture is heated for 20 minutes on the stream bath under reflux, and the reaction product is freed from water in vacuum at 60°C. The crude base is dissolved in 300 ml of methanol and hydrogenated with 2 previously reduced platinum oxide. After it has taken up the calculated quantity of hydrogen, the solvent is distilled off in vacuum, the residue dissolved in dilute hydrochloric acid and the neutral by-products are shaken out with ether. The aqueous solution is made alkaline with caustic soda and extracted with ether. From ethereal solution 13.2 g of the base are obtained with a boiling point at 1 mm of 128°-131°C.
25 g of 2-phenyl-3-aminobicyclo[2.2.1]heptane,15 g Raney nickel and 75 ml absolute alcohol are boiled under a reflux for 15 hours. The filtrate from the catalyst is neutralised with dilute hydrochloric acid and distilled to dryness in vacuum. The hydrochloric residue is purified by recrystallisation from acetone or dioxane-petrol-ether. Yield 21.5 g; MP: 191°C.
Therapeutic FunctionCentral stimulant, Anorexic
Fencamfamin Preparation Products And Raw materials
Raw materialsAcetaldehyde-->Platinum dioxide-->Aluminium-nickel
Tag:Fencamfamin(1209-98-9) Related Product Information
(2-CYCLOPENTYL-2-PHENYLETHYL)AMINE Fencamfamin FENCAMFAMINE HYDROCHLORIDE, DRUG STANDAR D SOLUTION Cypenamine 2-AMINONORBORNANE HYDROCHLORIDE