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lurasidone

lurasidone Suppliers list
Company Name:Shanghai Neosun Pharmaceutical Technology Co., Ltd.  Gold
Tel:021-20956531 18116226605
Email:neosunpharm@163.com
Company Name:Jinan Jianfeng Chemical Co., Ltd.   Gold
Tel:0531-88110457 83130510 83130502
Email:info@pharmachemm.com
Company Name:Chemvon Biotechnology Co., Ltd  Gold
Tel:+86-21-50790412
Email:marketing@chemvon.com
Company Name:Shanghai Boyle Chemical Co., Ltd.  
Tel:86-21-50180596
Email:sales@boylechem.com
Company Name:Chembest Research Laboratories Limited  
Tel:+86(0)21-20908456
Email:sales@biochembest.com; market@biochembest.com
lurasidone Basic information
Drug for the treatment of schizophrenia
Product Name:lurasidone
Synonyms:lurasidone;(3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione;4-{[(1R,2R)-2-{[4-(2$l^{4}-thia-6-azatricyclo[5.4.0.0^{2,6}]undeca-1(11),2,4,7,9-pentaen-5-yl)piperazin-1-yl]Methyl}cyclohexyl]Methyl}-4-azatricyclo[5.2.1.0^{2,6}]deca-1(9),2(6),7-triene-3,5-dione;Lurasidone (SM13496);(3aR,4S,7R,7aS)-2-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]Methyl}cyclohexyl]Methyl}hexahydro-1H-4,7-Methanoisoindole-1,3(2H)-dione;urasidone;Lurasidone, >=98%;Lurasidone Base
CAS:367514-87-2
MF:C28H36N4O2S
MW:0
EINECS:
Product Categories:Pharmaceutical intermediate
Mol File:Mol File
lurasidone Structure
lurasidone Chemical Properties
density 1.273
Safety Information
MSDS Information
lurasidone Usage And Synthesis
Drug for the treatment of schizophreniaLurasidone is developed by Japan's Dainippon Sumitomo Pharma which is an atypical antipsychotic,and is a classification of drug registration 3.1 class, it is suitable for the treatment of patients with schizophrenia. Its efficacy is Determined in four six weeks in adult patients with schizophrenia controlled studies. The exact mechanism of the treatment of schizophrenia, like other atypical antipsychotics ,is not very clear,and may be related to the antagonism of the dopamine D2 and serotonin 2A (5-HT2A) receptors. For the treatment of schizophrenia, a study has reported lurasidone can improve cognitive function.
October 28, 2010 ,the FDA approved lurasidone hydrochloride (lurasidone HCI) tablets once a day for the first-line treatment of patients with schizophrenia, the trade name is Latuda.
Dosage: The recommended starting dose is 40 mg / d, the effective dose range is 40 ~ 120 mg /· d, the maximum recommended dose is 80 mg /· d. It should be taken with food.
Adverse reaction: common adverse reactions are somnolence, akathisia, nausea, Parkinson's disease-like symptoms and emotional anxiety. Lurasidone has no physical dependence, less likely to cause weight gain, it does not cause glucose, lipids (lipids), it changs the period between ECG and QT.
The above information is edited by the Chemicalbook of Tian Ye.
lurasidone Preparation Products And Raw materials
Tag:lurasidone(367514-87-2) Related Product Information
Lurasidonhydrochloride