Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:CGP 53353;5,6-bis[(4-Fluorophenyl)aMino]-1H-isoindole-1,3(2H)-dione CAS:145915-60-2 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
EMMX Biotechnology LLC
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Tel: |
888-539-0666 |
Email: |
info@emmx.com |
Products Intro: |
Product Name:CGP 53353 CAS:145915-60-2 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Basic information |
Product Name: | 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE | Synonyms: | CGP 53353;5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE;5,6-BIS[(4-FLUOROPHENYL)AMINO]-2H-ISOINDOLE-1,3-DIONE;5,6-Bis[(4-fluorophenyl)amino]-2H-isoindole-1,3-dione, DAPH 2;DAPH 2;DAPH-7;PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem;1H-Isoindole-1,3(2H)-dione, 5,6-bis[(4-fluorophenyl)amino]- | CAS: | 145915-60-2 | MF: | C20H13F2N3O2 | MW: | 365.33 | EINECS: | | Product Categories: | Protein Kinase | Mol File: | 145915-60-2.mol | |
| 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Chemical Properties |
storage temp. | 2-8°C | solubility | DMSO: >10mg/mL | form | solid | color | orange |
| 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Usage And Synthesis |
Uses | CGP 53353 inhibited tyrosine kinase activity of the EGF-R in five different human transitional cell carcinoma lines. | Definition | ChEBI: 5,6-bis(4-fluoroanilino)isoindole-1,3-dione is a member of phthalimides. | Biological Activity | Selective inhibitor of PKC β II (IC 50 values are 0.41 and 3.8 μ M for PKC β II and PKC β I respectively). Also inhibits prionogenic Sup35 fibrillization (IC 50 ~ 3.4 μ M) and inhibits de novo A β 42 assembly in vitro . | storage | Store at RT |
| 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Preparation Products And Raw materials |
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