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| | 3,5-Dimethoxybenzoic acid Basic information |
| | 3,5-Dimethoxybenzoic acid Chemical Properties |
| Melting point | 178-180 °C (lit.) | | Boiling point | 275.56°C (rough estimate) | | density | 1.2481 (rough estimate) | | refractive index | 1.4500 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | almost transparency in hot Methanol | | form | Crystalline Powder | | pka | 3.96±0.10(Predicted) | | color | Almost white to light beige-pink | | BRN | 511834 | | InChIKey | IWPZKOJSYQZABD-UHFFFAOYSA-N | | LogP | 2.190 | | CAS DataBase Reference | 1132-21-4(CAS DataBase Reference) | | NIST Chemistry Reference | 3,5-Dimethoxybenzoic acid(1132-21-4) | | EPA Substance Registry System | Benzoic acid, 3,5-dimethoxy- (1132-21-4) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Hazard Note | Irritant | | TSCA | Yes | | HS Code | 29189090 |
| | 3,5-Dimethoxybenzoic acid Usage And Synthesis |
| Chemical Properties | almost white to light beige-pink cryst. powder | | Uses | 3,5-Dimethoxybenzoic acid (3,5-DmeoxBA) can be used as a reactant for the synthesis of:
- 5,7-Dimethoxy-3,4-diphenylisocoumarin by coupling with diphenylacetylene.
- Biotin dimedone, a reagent used in the study of protein sulfenation.
It can also be used as a ligand to synthesize lanthanide complexes [Ln(3,5-DmeoxBA)3(phen)]2; where phen is 1,10-phenanthroline. | | Definition | ChEBI: 3,5-dimethoxybenzoic acid is a methoxybenzoic acid that is benzoic acid which is substituted by methoxy groups at positions 3 and 5. It has a role as a plant metabolite. It is a conjugate acid of a 3,5-dimethoxybenzoate. | | Purification Methods | Crystallise the acid from water, EtOH or aqueous acetic acid and dry it in a vacuum. [Beilstein 10 H 405, 10 I 195, 10 III 1446, 10 IV 1501.] |
| | 3,5-Dimethoxybenzoic acid Preparation Products And Raw materials |
| Raw materials | Dimethyl sulfate-->3,5-Dihydroxybenzoic acid | | Preparation Products | Brodimoprim-->Methyl 3,5-dimethoxybenzoate-->1-Bromo-3,5-dimethoxybenzene-->5-propylbenzene-1,3-diol-->Methyl 3,5-dihydroxyphenylacetate-->3,5-DIMETHOXYBENZOYL CHLORIDE-->3,5-Dimethoxybenzyl chloride-->RVX-208-->5-(3,5-DIMETHOXYPHENYL)-1,3,4-OXADIAZOLE-2-THIOL-->3,5-DIMETHOXY-1-METHYLCYCLOHEXA-2,5-DIENECARBOXYLIC ACID |
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