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| | 1-METHOXY-4-NITRONAPHTHALENE Basic information |
| | 1-METHOXY-4-NITRONAPHTHALENE Chemical Properties |
| Melting point | 83-85 °C (lit.) | | Boiling point | 341.49°C (rough estimate) | | density | 1.2621 (rough estimate) | | refractive index | 1.4950 (estimate) | | storage temp. | Sealed in dry,Room Temperature |
| | 1-METHOXY-4-NITRONAPHTHALENE Usage And Synthesis |
| Chemical Properties | yellow to orange crystalline powder | | Uses | 1-Methoxy-4-nitronaphthalene is used as a reagent in the synthesis of UMI-77 (U700850); a small molecule inhibitor of Mcl-1 which blocks and attenuates pancreatic cell cancer growth. Also an anticancer agent. | | Synthesis Reference(s) | Synthesis, p. 70, 1985 DOI: 10.1055/s-1985-31110 | | Purification Methods | Purify it by chromatography on silica gel, then recrystallise it from MeOH or EtOH (yellow needles). [Hodgson & Habeshaw J Chem Soc 47 1942, Bunce et al. J Org Chem 52 4214 1987, Beilstein 6 H 616, 6 III 2938.] |
| | 1-METHOXY-4-NITRONAPHTHALENE Preparation Products And Raw materials |
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