- 3-CYANO-7-ETHOXYCOUMARIN
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- $1.10 / 1g
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2021-11-02
- CAS:117620-77-6
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons Min
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| | 3-CYANO-7-ETHOXYCOUMARIN Basic information |
| | 3-CYANO-7-ETHOXYCOUMARIN Chemical Properties |
| Melting point | 210-212°C | | Boiling point | 396.8±42.0 °C(Predicted) | | density | 1.29±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble | | form | Solid | | color | yellow to orange | | λmax | 356 nm (Buffer pH7); 355 nm(MeOH) | | Biological Applications | As a substrate for
measuring cytochrome P450 enzymes activity;
cytochrome P450 inhibition assays;
drug design;
drug metabolism;
treating viral or parasite
infections. |
| | 3-CYANO-7-ETHOXYCOUMARIN Usage And Synthesis |
| Uses | Substrate for determination of cytochrom P-450 dependent oxidases; about 50-100 times more sensitive than conventional substrate ethoxy-resorufin due to higher turn over rate. | | Uses | 3-Cyano-7-ethoxycoumarin has been used as a substrate in cytochrome P (CYP) inhibition for fluorescence measurement. | | General Description | 3-Cyano-7-ethoxycoumarin is a fluorescent substrate for Cytochrome P450 1A1 (CYP1A1), Cytochrome P450 1A2 (CYP1A2), Cytochrome P450 2C9 (CYP2C9) and Cytochrome P450 2C19 (CYP2C19). | | Biochem/physiol Actions | Fluorescent probe useful in microsomal dealkylase studies. Typical drug-drug interactions resulting from enzyme inhibition. |
| | 3-CYANO-7-ETHOXYCOUMARIN Preparation Products And Raw materials |
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