Company Name: |
J & K SCIENTIFIC LTD.
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Tel: |
010-82848833 400-666-7788 |
Email: |
jkinfo@jkchemical.com |
Products Intro: |
Product Name:BroMindione CAS:1146-98-1 Package:100Mg,1g
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| Bromindione Basic information |
| Bromindione Chemical Properties |
Melting point | 139-142°C | density | 1.4993 (rough estimate) | refractive index | 1.4650 (estimate) | storage temp. | Amber Vial, -20°C Freezer | solubility | Chloroform, Methanol | form | Solid | color | Black | Stability: | Light Sensitive |
RIDADR | 2811 | HazardClass | 6.1(b) | PackingGroup | III | HS Code | 2914199090 | Toxicity | LD50 oral in mouse: 200mg/kg |
| Bromindione Usage And Synthesis |
Chemical Properties | Black Solid | Originator | Bromindione,Chemical
Formulations | Uses | antidiabetic | Uses | Anticoagulant. | Definition | ChEBI: Bromindione is a member of indanones and a cyclic ketone. | Manufacturing Process | To a solution of 1.85 g of sodium in 40 ml of ethanol, was added 10 g of
phthalide and 14.0 g of p-bromobenzaldehyde, and the reaction mixture was
heated on the steam bath for one hour. Water was then added, and the
alcohol was distilled off. Then after adding additional water, the reaction
mixture was acidified with hydrochloric acid to precipitate the crude product,
which was filtered off, dried and recrystallized from methanol. The 2-pbromophenylindandione
is in the form of dark red crystals, having a melting
point of 133-135°C. | Therapeutic Function | Anticoagulant |
| Bromindione Preparation Products And Raw materials |
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