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| | GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA Basic information |
| Product Name: | GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA | | Synonyms: | GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA;[ALA107]-MBP (104-118);[ALA107]-MBP FRAGMENT 104-118;[ALA107]-MYELIN BASIC PROTEIN FRAGMENT 104-118;[Ala107]-Myelin Basic Protein (104-118);(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[2-[[(2S)-6-amino-2-[(2-aminoacetyl)amino]hexanoyl]amino]acetyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]acetyl]amino]propanoic acid;L-Alanine, glycyl-L-lysylglycyl-L-alanylglycyl-L-leucyl-L-seryl-L-leucyl-L-seryl-L-arginyl-L-phenylalanyl-L-seryl-L-tryptophylglycyl- (9CI);GKGAGLSLSRFSWGA | | CAS: | 99026-77-4 | | MF: | C67H104N20O19 | | MW: | 1493.67 | | EINECS: | | | Product Categories: | Protein Kinase | | Mol File: | 99026-77-4.mol |  |
| | GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA Chemical Properties |
| storage temp. | −20°C | | solubility | Soluble to 1 mg/ml in 10% acetonitrile | | form | solid | | color | White | | Sequence | H-Gly-Lys-Gly-Ala-Gly-Leu-Ser-Leu-Ser-Arg-Phe-Ser-Trp-Gly-Ala-OH |
| | GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA Usage And Synthesis |
| Biological Activity | [ala107]-mbp (104-118) is a non-competitive inhibitor of pkc and synthetic peptide analog of bovine myelin basic protein (mbp) with ic50 value of 46 - 145 mm.1. substrate specificity of phospholipid/ca2+ dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein. turner et al. j.biol.chem., 1985;260:115032. synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase c). su et al. biochem.biophys.res.commun., 1986;134:78 | | Biochem/physiol Actions | [Ala107]-Myelin Basic Protein Fragment 104-118 is an inhibitor of protein kinase C. |
| | GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA Preparation Products And Raw materials |
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