(+)-脱落酸
| 中文名称 | (+)-脱落酸 |
|---|---|
| 中文同义词 | 5-(1-羟基-2,6,6-三甲基-4-氧-2-环己-1-烯基-3-甲基-2,4-戊二烯酸;脱落素Ⅱ;休眠酸;ABSCISIC ACID 脱落;脱;天然脱落酸,2-顺式,4-反式-5-(1-羟基-4-氧代-2,6,6-三甲基-2-环己烯-1-基)-3-甲基-2,4-戌二烯酸;S-诱抗素;诱抗素 |
| 英文名称 | (+)-Abscisic acid |
| 英文同义词 | (ABA)ABSCISIC ACID >98%;(+)-Abscisic acid;ABA, Dormin, (S)-5-(1-Hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3-methyl-(2Z,4E)-pentadienoic acid;S-(+)-ABA;(S)-(+)-ABSCISIC ACID;[S]-5-[1-HYDROXY-2,6,6-TRIMETHYL-4-OXOCYCLOHEX-2-EN-1-YL]-3-METHYL-[2Z,4E]-PENTADIENOIC ACID;(+)-abscisinii;(+)-cis-abscisicacid |
| CAS号 | 21293-29-8 |
| 分子式 | C15H20O4 |
| 分子量 | 264.32 |
| EINECS号 | 244-319-5 |
| 相关类别 | 植物生化提取物;小分子抑制剂，天然产物;植物激素及核酸类;植物生长激素;营养学研究;生化试剂;对照品;医药原料药-科研原料;plantgrowth;农用原药-原药;有机原料;高纯生化试剂;生化试剂-植物激素及核酸类;农用化学品原料;原料;农药;化妆品原料;其他原料;化学试剂;化工原料;科研精品试剂;其它;有机化工原料;生物缓冲液系列;Pharmaceutical Raw Materials;Sesqui-Terpenoids;Chiral Reagents;Biochemistry;Plant Growth Regulators;Plant Growth Trgulators (Others);Plant Hormones;Agro-Products;Inhibitors;Plant Growth regulator |
| Mol文件 | 21293-29-8.mol |
| 结构式 |  |
(+)-脱落酸 性质
| 熔点 | 188 °C |
|---|---|
| 比旋光度 | D20 +411.1° (c = 1 in ethanol); D20 +426.5° (c = 1 in 0.005N methanolic H2SO4) |
| 沸点 | 327.55°C (rough estimate) |
| 密度 | 1.0583 (rough estimate) |
| 折射率 | 410 ° (C=0.2, EtOH) |
| 储存条件 | 2-8°C |
| 溶解度 | 氯仿（微溶）、乙醇（微溶）、甲醇（微溶） |
| 酸度系数(pKa) | 4.87±0.33(Predicted) |
| 形态 | 类白色粉末 |
| 颜色 | 白色至浅黄色 |
| 旋光性 (optical activity) | [α]/D 415±10°, c = 0.1 in ethanol |
| Merck | 14,11 |
| BRN | 2698956 |
| 稳定性 | 感光 |
| InChIKey | JLIDBLDQVAYHNE-WEYXYWBQSA-N |
| LogP | 1.896 (est) |
| CAS 数据库 | 21293-29-8(CAS DataBase Reference) |
| EPA化学物质信息 | 2,4-Pentadienoic acid, 5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl]-3-methyl-, (2Z,4E)- (21293-29-8) |
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Human Endogenous Metabolite
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In Arabidopsis cell cultures, Abscisic acid ((S)-(+)-Abscisic acid; 10 μM) simultaneously induces rapid alkalinization of the medium and plasma membrane depolarization.
Abscisic acid (10 μM) increases Ca
2+
in cytosol of Arabidopsis cell suspension. Abscisic acid does not inhibit proton pumping directly but through an increase in cytosolic Ca
2+
.
Lanthionine synthetase C-like 2 (LANCL2) is the natural receptor for Abscisic acid. Abscisic acid, both at the organism levels and in specific muscle cells ex vivo, increases both glucose and fatty acid metabolism in the mitochondria, increases glycogen synthesis, activates PI3K independently of insulin and promotes GLUT4 translocation to the cell membrane.
Abscisic acid (orally; 0.125 µg/kg/day; for 12 weeks) improves glycemic control.
Abscisic acid (orally; 0.125 µg/kg/day; for 12 weeks) results in significantly lower levels of TNF, MCP-1 and IL-6 in the DIO model. Abscisic acid increases metabolic activity in skeletal muscle.
| Animal Model: | Diet-induced obesity (DIO) mice at 4 weeks of age |
| Dosage: | 0.125 µg/kg |
| Administration: | Orally; daily; for 12 weeks |
| Result: | Improved glycemic control in a diet-induced model of obesity |
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| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/16 | XW212932986 | (+)-脱落酸 | 21293-29-8 | 100MG | 93元 |
| 2024/01/16 | S7594 | (+)-脱落酸 Abscisic Acid (Dormin) | 21293-29-8 | 5mg | 809.55元 |