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| 2-Bromo-5-fluorobenzonitrile Basic information |
| 2-Bromo-5-fluorobenzonitrile Chemical Properties |
Melting point | 92-95 °C(lit.) | Boiling point | 251.2±25.0 °C(Predicted) | density | 1.69±0.1 g/cm3(Predicted) | storage temp. | Sealed in dry,Room Temperature | solubility | Soluble in methanol. | form | powder to crystal | color | White to Yellow to Orange | BRN | 8678330 | InChIKey | MDHNVHCZDCSTMS-UHFFFAOYSA-N | CAS DataBase Reference | 57381-39-2(CAS DataBase Reference) |
Hazard Codes | Xn,T,Xi | Risk Statements | 20/21/22 | Safety Statements | 26-36 | RIDADR | 3439 | WGK Germany | 3 | Hazard Note | Toxic | HazardClass | 6.1 | PackingGroup | III | HS Code | 29269090 |
| 2-Bromo-5-fluorobenzonitrile Usage And Synthesis |
Chemical Properties | Colorless solid | Uses | 2-Bromo-5-fluorobenzonitrile may be used in the preparation of 5-chloro-4,2?-difluorobiphenyl-2-carbonitrile. | Uses | 2-Bromo-5-fluorobenzonitrile is used in the synthesis of pyrimidine functional compounds acting as GABAAα2/α3 binding site agonists used in the treatment of anxiety disorders. | General Description | 2-Bromo-5-fluorobenzonitrile can be prepared from 3-fluorobenzonitrile vial bromination using 1,3-dibromo-5,5-dimethylhydantoin (DBDMH).. It undergoes palladium-catalyzed Suzuki coupling with boronic acid derivative to form corresponding biaryl. |
| 2-Bromo-5-fluorobenzonitrile Preparation Products And Raw materials |
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