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| | 5BETA-PREGNANE-3ALPHA,20ALPHA-DIOL Basic information |
| Product Name: | 5BETA-PREGNANE-3ALPHA,20ALPHA-DIOL | | Synonyms: | 3-alpha,20-alpha-dihydroxy-5-beta-pregnan;3-alpha,20-alpha-dihydroxy-5-beta-pregnane;5BETA-PREGNANE-3ALPHA,20ALPHA-DIOL;5B-PREGNANE-3A,20A-DIOL;5BETA-PREGNAN-3A,20A-DIOL;5-BETA-PREGNAN-3-ALPHA, 20-ALPHA-DIOL;PREGNANEDIOL;PREGNANDIOL | | CAS: | 80-92-2 | | MF: | C21H36O2 | | MW: | 320.51 | | EINECS: | 201-313-7 | | Product Categories: | Inhibitors;Steroids;Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Biochemistry;Hydroxysteroids | | Mol File: | 80-92-2.mol |  |
| | 5BETA-PREGNANE-3ALPHA,20ALPHA-DIOL Chemical Properties |
| Melting point | 240-242°C | | alpha | D20 +27.4° (c = 0.7 in alc) | | Boiling point | 399.39°C (rough estimate) | | density | 1.1500 | | refractive index | 27 ° (C=0.5, EtOH) | | storage temp. | Sealed in dry,2-8°C | | solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) | | form | Solid | | pka | 15.05±0.20(Predicted) | | color | White to Off-White | | Merck | 7727 |
| | 5BETA-PREGNANE-3ALPHA,20ALPHA-DIOL Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | Labelled 5β-Pregnane-3α,20α-diol, a metabolite of Progesterone (P755900). | | Uses | 5β-Pregnane-3α,20α-diol is a metabolite of Progesterone (P755900). | | Uses | Progesterone metabolite | | Definition | ChEBI: Pregnanediol is a corticosteroid hormone. It is a tautomer of a 5beta-pregnane-3beta,20alpha-diol. | | Purification Methods | Crystallise the diol from acetone. The diacetate [1174-69-2] crystallises from pet ether with m 180o (also 182183o) and [] D 20 +35o (c 1.1, CHCl3). [Marian Biochem J 23 1090 1929, Fish et al. J Biol Chem 143 716 1942, Hieschmann J Biol Chem 140 797 1941, Johnson et al. J Chem Soc 1302 1954, Glick et al. J Org Chem 27 3121 1962, Beillstein 6 III 4778, 6 IV 6111.] |
| | 5BETA-PREGNANE-3ALPHA,20ALPHA-DIOL Preparation Products And Raw materials |
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