- Isoxazole
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- $1.00 / 1KG
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2019-07-06
- CAS:288-14-2
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 100KG
Related articles - Isoxazole
- ?Isoxazoles belong to an important class of five-membered aromatic heterocycles containing two electronegative heteroatoms, ni....
- Apr 11，2023
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| | Isoxazole Basic information |
| | Isoxazole Chemical Properties |
| Melting point | -67.1°C | | Boiling point | 93-95 °C(lit.) | | density | 1.078 g/mL at 25 °C(lit.) | | vapor density | 2.4 (vs air) | | refractive index | n20/D 1.427(lit.) | | Fp | 48 °F | | storage temp. | 2-8°C | | solubility | 167g/l | | pka | -2.0(at 25℃) | | form | clear liquid | | color | Colorless to Light yellow | | BRN | 103773 | | InChIKey | CTAPFRYPJLPFDF-UHFFFAOYSA-N | | CAS DataBase Reference | 288-14-2(CAS DataBase Reference) | | NIST Chemistry Reference | Isoxazole(288-14-2) | | EPA Substance Registry System | Isoxazole (288-14-2) |
| Hazard Codes | F,Xi | | Risk Statements | 11 | | Safety Statements | 16-23/33-33-29-7/9 | | RIDADR | UN 1993 3/PG 2 | | WGK Germany | 3 | | F | 10 | | Hazard Note | Highly Flammable | | TSCA | Yes | | HazardClass | 3 | | PackingGroup | II | | HS Code | 29349990 |
| | Isoxazole Usage And Synthesis |
| Description | Isoxazole, an important class of heterocycles, is a five membered heterocyclic compound that exhibits various pharmacological actions. It is present in some natural products such as ibotenic acid and is also used as a foundation for several drugs such as the COX-2 inhibitor valdecoxib and anti-inflammatory drugs. Isoxazoles are largely applied in the area of pharmaceuticals and therapeutics, including insecticidal, antibacterial, antibiotic, antitumour, antifungal, antituberculosis, anticancer and ulcerogenic. Besides, it has a great effect on reducing blood glucose, eliminating pain, resisting inflammation, killing harmful bacteria, controlling and reducing the risk of HIV. | | Chemical Properties | A colorless liquid resembling pyridine. It is soluble in water at room temperature up to six times its volume. | | Uses | Natural insecticide. | | Definition | ChEBI: Isoxazole is a monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles. It is a mancude organic heteromonocyclic parent, a monocyclic heteroarene and a member of isoxazoles. | | Preparation | Isoxazoles can be synthesized by various methods, such as the 1,3-dipolar cycloaddition reaction of nitrile oxides with alkynes, the reaction of hydroxylamine with 1,3-diketones or propiolic acid derivatives, etc.
www.organic-chemistry.org | | General Description | Isoxazole(288-14-2) are described as inhibitors of acetylcholinesterase (AChE). Isoxazole ligands bind to and inhibit the Sxc- antiporter. | | Hazard | Narcotic and psychomimetic effects. | | References | https://en.wikipedia.org/wiki/Isoxazole
https://pubchem.ncbi.nlm.nih.gov/compound/9254 |
| | Isoxazole Preparation Products And Raw materials |
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