- Anti-cancer Activity
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- $1.00 / 1KG
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2019-12-24
- CAS:50980-32-0
- Min. Order: 1KG
- Purity: 85.0-99.8%
- Supply Ability: 20 tons
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| Product Name: | ANKAFLAVIN | | Synonyms: | ANKAFLAVIN;Anti-cancer Activity;2H-Furo[3,2-g][2]benzopyran-2,9(3H)-dione, 3a,4,8,9a-tetrahydro-9a-methyl-3-(1-oxooctyl)-6-(1E)-1-propen-1-yl-, (3S,3aR,9aR)- | | CAS: | 50980-32-0 | | MF: | C23H30O5 | | MW: | 386.48 | | EINECS: | | | Product Categories: | | | Mol File: | 50980-32-0.mol |  |
| | ANKAFLAVIN Chemical Properties |
| Boiling point | 590.7±50.0 °C(Predicted) | | density | 1.15±0.1 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | Soluble in DMSO | | pka | 10.75±0.60(Predicted) |
| | ANKAFLAVIN Usage And Synthesis |
| Description | Ankaflavin (AK), isolated from Monascus-Fermented red rice, is a PPARγ agonist with anti-inlfammatory activity. Ankaflavin is an active compound having anti-inflammatory, anti-cancer, antiatherosclerotic, and hypolipidemic effects.
| | Anti-cancer Activity | Ankaflavin was found to be toxic to human cancer cell lines Hep G2 and A549 with a similar IC50 value of 15 μg/mL, while it posed no significant toxicity to normal MRC-5 and WI-38 cells at the same concentration.Ankaflavin exhibits selective cytotoxic effect and induces cell death on cancer cells.
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| | ANKAFLAVIN Preparation Products And Raw materials |
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