| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:CarboMycin
CAS:4564-87-8
Package:50Mg,5Mg
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| Company Name: |
Chemsky (shanghai) International Co.,Ltd
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| Tel: |
021-50135380 |
| Email: |
shchemsky@sina.com |
| Products Intro: |
Product Name:CarboMycin;(12S,13S)-9-Deoxy-12,13-epoxy-12,13-dihydro-9-oxoleucoMycin V 3-Acetate 4B-(3-Methylbutanoate); CarboMycin A; CarboMycin; DeltaMycin A4; M 4209; MagnaMycin; MagnaMycin A; NSC 51001; NSC 55924;
CAS:4564-87-8
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Carbomycin A
CAS:4564-87-8
Remarks:It is produced by the strain of Streptomyces halstedii. It is mainly resistant to gram-positive bact
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| | carbomycin Basic information |
| Product Name: | carbomycin | | Synonyms: | carbomycin;3-Methyl-butyric acid 6-{[(Z)-7-acetoxy-8-methoxy-3,12-dimethyl-5,13-dioxo-10-(2-oxo-ethyl)-4,17-dioxa-bicyclo[14.1.0]heptadec-14-en-9-yloxy]-dimethylamino-hydroxy-methyl-tetrahydro-pyran-3-yloxy}-4-hydroxy-2,4-dimethyl-tetrahydro-pyran-3-yl ester;Aids012086;Aids-012086;Magnamycin a;Nsc51001;(12S,13S)-9-Deoxy-12,13-epoxy-12,13-dihydro-9-oxoleucoMycin V 3-Acetate 4B-(3-Methylbutanoate);CarboMycin A | | CAS: | 4564-87-8 | | MF: | C42H67NO16 | | MW: | 841.982 | | EINECS: | | | Product Categories: | Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 4564-87-8.mol |  |
| | carbomycin Chemical Properties |
| Melting point | 214° | | alpha | D25 -58.6° (chloroform) | | Boiling point | 769.45°C (rough estimate) | | density | 1.1761 (rough estimate) | | refractive index | 1.6220 (estimate) | | pka | pKb 7.2(at 25℃) |
| Toxicity | LD50 i.v. in mice: 550 mg/kg (Tanner) |
| | carbomycin Usage And Synthesis |
| Originator | Magnamycin,Pfizer,US,1953 | | Uses | Sixteen-membered-ring macrolite antibiotic complex similar to Leucomycin and Erythromycin, produced by Stroptomyces halstedii. | | Definition | An antibiotic isolated from products of Strepto-
myces halstedii when grown in suitable media
by the deep-culture method. It inhibits growth of
certain gram-positive bacteria such as staphylo-
cocci, pneumococci, and hemolytic streptococci. | | Manufacturing Process | A selected strain of Streptomyces halstedii was cultivated in an aqueous
nutrient medium under aerobic conditions and the resulting broth containing
carbomycin antibiotics was filtered. The solutions was extracted twice at pH
6.5 with one-quarter volume of methyl isobutyl ketone. The combined extracts
were concentrated to one-tenth volume under vacuum, and the antibiotics
were extracted into water adjusted to a pH of about 2 with sulfuric acid. After
adjusting the separated aqueous solution to pH 6.5, the antibiotic was
extracted into benzene and the solution was concentrated to a small volume.
Addition of hexane resulted in the separation of a solid product containing the
benzene complexes of carbomycin A and carbomycin B, present in the
fermentation broth. | | Brand name | Magnamycin
(Pfizer). | | Therapeutic Function | Antibiotic | | Safety Profile | Poison by
subcutaneous route. Moderately toxic by
intravenous and intramuscular routes. When
heated to decomposition it emits toxic
fumes of NOx. |
| | carbomycin Preparation Products And Raw materials |
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