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| | n-Octyl-β-D-glucopyranoside Basic information |
| | n-Octyl-β-D-glucopyranoside Chemical Properties |
| Melting point | 105 °C | | Boiling point | 354.3°C (rough estimate) | | alpha | -32 º (c=5, water) | | density | 1.0869 (rough estimate) | | refractive index | -27 ° (C=1, MeOH) | | storage temp. | -20°C | | solubility | DMSO (Slightly), Water (Slightly) | | pka | 12.95±0.70(Predicted) | | form | Crystalline Powder and Chunks | | color | White | | Water Solubility | 3 g/10 mL | | Sensitive | Hygroscopic | | Merck | 14,6767 | | BRN | 84118 | | Stability: | Hygroscopic | | InChIKey | HEGSGKPQLMEBJL-QNOVJUQQSA-N | | LogP | 0.887 (est) | | CAS DataBase Reference | 29836-26-8(CAS DataBase Reference) | | EPA Substance Registry System | Octyl .beta.-D-glucopyranoside (29836-26-8) |
| Risk Statements | 36/37/38 | | Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29400090 |
| | n-Octyl-β-D-glucopyranoside Usage And Synthesis |
| Description | n-Octyl-β-D-glucopyranoside is a non–ionic detergent intended for solubilizing membrane–bound proteins in their native state and for the preparation of lipid vesicles. n-Octyl-β-D-glucopyranoside has a well–defined chemical structure, small uniform micelles, and high water solubility, which make n-Octyl-β-D-glucopyranoside superior to most other nonionic detergents for membrane solubilization. Because of the high critical micelle concentration (20-25 mM), n-Octyl-β-D-glucopyranoside has the additional advantage of being removed easily by dialysis when compared to bile salts. n-Octyl-β-D-glucopyranoside is also known as N-Octyl glucoside, OGP, OG, n-Octylglucoside, and octyl-β-D-glucopyranoside.
| | Chemical Properties | white crystalline powder and chunks | | Uses | Unlike many other detergents, octyl glucoside is a pure, single compound of defined structure. Very effective for insulin binding and solubilization studies of membran | | Uses | A nonionic detergent for the solubilization of membrane bound protein. | | Uses | Detergent and surfactant for biological systems. | | Definition | ChEBI: Octyl beta-D-glucopyranoside is an beta-D-glucoside in which the anomeric hydrogen of beta-D-glucopyranose is substituted by an octyl group. It has a role as a plant metabolite. | | Purification Methods | Purify n-Octyl-β-D-glucopyranoside by recrystallisation from Me2CO. It is hygroscopic and should be stored in a well-stoppered container. [Noller & Rockwell J Am Chem Soc 6 0 2076 1938, Pigman & Richtmyer J Am Chem Soc 64 369 1942.] It is a UV transparent non-ionic dialysable detergent for solubilising membrane proteins. The D-isomer with [] D 20 +118o (c 1, MeOH) has similar solubilising properties. [Lazo & Quinn Anal Biochem 102 68 1980, Stubbs et al. Biochim Biophys Acta 426 46 1976, Beilstein 17/7 V 38.] |
| | n-Octyl-β-D-glucopyranoside Preparation Products And Raw materials |
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